p-cymene

Modify Date: 2024-01-02 17:24:09

p-cymene Structure
p-cymene structure
Common Name p-cymene
CAS Number 99-87-6 Molecular Weight 134.218
Density 0.9±0.1 g/cm3 Boiling Point 173.9±10.0 °C at 760 mmHg
Molecular Formula C10H14 Melting Point -68 °C
MSDS Chinese USA Flash Point 47.2±0.0 °C
Symbol GHS02 GHS08 GHS09
GHS02, GHS08, GHS09
Signal Word Danger

 Use of p-cymene


p-Cymene is a monoterpene that has diverse biological activities, including antimicrobial, anticancer, antioxidant, anti-inflammatory, antinociceptive, and anxiolytic properties[1].

 Names

Name p-cymene
Synonym More Synonyms

 p-cymene Biological Activity

Description p-Cymene is a monoterpene that has diverse biological activities, including antimicrobial, anticancer, antioxidant, anti-inflammatory, antinociceptive, and anxiolytic properties[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Marchese A, et al. Update on Monoterpenes as Antimicrobial Agents: A Particular Focus on p-Cymene. Materials (Basel). 2017 Aug 15;10(8):947.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 173.9±10.0 °C at 760 mmHg
Melting Point -68 °C
Molecular Formula C10H14
Molecular Weight 134.218
Flash Point 47.2±0.0 °C
Exact Mass 134.109543
LogP 4.02
Vapour density 4.62 (vs air)
Vapour Pressure 1.7±0.2 mmHg at 25°C
Index of Refraction 1.493
Stability Stable. Flammable. Incompatible with strong oxidizing agents, strong acids, strong bases.
Water Solubility PRACTICALLY INSOLUBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ5950000
CHEMICAL NAME :
p-Cymene
CAS REGISTRY NUMBER :
99-87-6
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C10-H14
MOLECULAR WEIGHT :
134.24
WISWESSER LINE NOTATION :
1Y1&R D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,401,1974 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4750 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - chromodacryorrhea Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 25 ppm (140 mg/m3);STEL 35 ppm (190 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8309 No. of Facilities: 8820 (estimated) No. of Industries: 96 No. of Occupations: 81 No. of Employees: 176382 (estimated) No. of Female Employees: 39063 (estimated)

 Safety Information

Symbol GHS02 GHS08 GHS09
GHS02, GHS08, GHS09
Signal Word Danger
Hazard Statements H226-H304-H411
Precautionary Statements P210-P301 + P310-P331-P370 + P378
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R10;R36/37/38
Safety Phrases S26-S36
RIDADR UN 2046 3/PG 3
WGK Germany 2
RTECS GZ5950000
Packaging Group III
Hazard Class 3
HS Code 2902909090

 Synthetic Route

 Customs

HS Code 2902909090
Summary 2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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 Synonyms

Benzene, 1-methyl-4- (1-methylethyl)-
Benzene, 1-methyl-4-(1-methylethyl)-
p-methyl cumene
p-Isopropyltoluene (p-Cymene)
EINECS 202-796-7
para-cymene
4-methyl-1-(propan-2-yl)benzene
1-methyl-4-(propan-2-yl)benzene
p-methyl-Cumene
Cymene, p-
1-Methyl-4-(1-methylethyl)-benzene
4-methyl isopropylbenzene
1-Isopropyl-4-methylbenzene
p-isopropyltoluene
4-Isopropyltoluene
1-isopropyl-4-methyl-Benzene
Cymene
p-methylcumene
Cumene, p-methyl-
p-Mentha-1,3,5-triene
MFCD00008893
4-cymene
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