Ethylene methacrylate

Modify Date: 2024-01-02 12:09:32

Ethylene methacrylate Structure
Ethylene methacrylate structure
Common Name Ethylene methacrylate
CAS Number 97-90-5 Molecular Weight 198.216
Density 1.0±0.1 g/cm3 Boiling Point 260.6±13.0 °C at 760 mmHg
Molecular Formula C10H14O4 Melting Point -40 °C
MSDS Chinese USA Flash Point 121.8±18.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Ethylene methacrylate


Ethylene glycol dimethacrylate is a methacrylate monomer, exhibits cytotoxic and genotoxic effects on human gingival fibroblasts (HGFs). Ethylene glycol dimethacrylate increases intracellular reactive oxygen species (ROS) production, causes DNA damage, increases apoptosis and causes cell cycle arrest in G1/G0 phase[1].

 Names

Name ethylene glycol dimethacrylate
Synonym More Synonyms

 Ethylene methacrylate Biological Activity

Description Ethylene glycol dimethacrylate is a methacrylate monomer, exhibits cytotoxic and genotoxic effects on human gingival fibroblasts (HGFs). Ethylene glycol dimethacrylate increases intracellular reactive oxygen species (ROS) production, causes DNA damage, increases apoptosis and causes cell cycle arrest in G1/G0 phase[1].
Related Catalog
References

[1]. Anna Bielecka-Kowalska, et al. Ethylene glycol dimethacrylate and diethylene glycol dimethacrylate exhibits cytotoxic and genotoxic effect on human gingival fibroblasts via induction of reactive oxygen species. Toxicol In Vitro. 2018 Mar:47:8-17.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 260.6±13.0 °C at 760 mmHg
Melting Point -40 °C
Molecular Formula C10H14O4
Molecular Weight 198.216
Flash Point 121.8±18.2 °C
Exact Mass 198.089203
PSA 52.60000
LogP 2.78
Vapour density >1 (vs air)
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.449
Stability Unstable - may polymerize upon exposure to light. Incompatible with strong acids, strong oxidizing agents, strong bases.
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OZ4400000
CHEMICAL NAME :
Methacrylic acid, ethylene ester
CAS REGISTRY NUMBER :
97-90-5
BEILSTEIN REFERENCE NO. :
1776663
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C10-H14-O4
MOLECULAR WEIGHT :
198.24
WISWESSER LINE NOTATION :
1UY1&VO2OVY1&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
5820 umol/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17,264,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3204 No. of Facilities: 983 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 6295 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3204 No. of Facilities: 562 (estimated) No. of Industries: 8 No. of Occupations: 14 No. of Employees: 9073 (estimated) No. of Female Employees: 3604 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317-H335
Precautionary Statements P280-P304 + P340 + P312-P333 + P313
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R37;R43
Safety Phrases S24-S37
RIDADR UN3334 9
WGK Germany 1
RTECS OZ4400000
Hazard Class 9.0
HS Code 2916140000

 Synthetic Route

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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 Synonyms

Ethylene methacrylate
Ethylene dimethacrylate
Glycol dimethacrylate
Ethane-1,2-diyl bis(2-methylprop-2-enoate)
1UY1&VO2OVY1&U1
MFCD00008590
2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester
Ethyldiol methacrylate
Ethane-1,2-diyl bis(2-methylacrylate)
EINECS 202-617-2
1,2-Ethanediyl bis(2-methylacrylate)
Methacrylic acid ethylene ester
1,2-Ethanediol dimethacrylate
Ethylene glycol dimethacrylate
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