OXA-01

Modify Date: 2024-02-05 16:07:32

OXA-01 structure	Common Name	OXA-01
	CAS Number	936889-68-8	Molecular Weight	409.86900
	Density	1.61±0.1 g/cm3 (20 °C, 760 mmHg)	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₀ClN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of OXA-01

OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC50 values of 29 nM and 7 nM, respectively[1].

Name	Cyclohexanecarboxylic acid, 4-[8-amino-1-(7-chloro-1H-indol-2-yl)imidazo[1,5-a]pyrazin-3-yl]-, trans

Description	OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC50 values of 29 nM and 7 nM, respectively[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer
In Vivo	OXA-01 demonstrated broad anti-tumor activity in several different human xenograft models of various histologies. Furthermore, in GEO and Colo-205 colon xenograft models, OXA-01 demonstrated 100% TGI, whilst rapamycin treatment resulted in only 75% and 53% TGI, respectively[1].
References	[1]. OXA-01 displays improved anti-tumor activity in comparison to Rapamycin.

Density	1.61±0.1 g/cm3 (20 °C, 760 mmHg)
Molecular Formula	C₂₁H₂₀ClN₅O₂
Molecular Weight	409.86900
Exact Mass	409.13100
PSA	109.30000
LogP	5.05280

DC Chemicals Limited
China
Product Name: OXA-01
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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