Iodoacetyl-LC-biotin

Modify Date: 2024-01-28 11:27:11

Iodoacetyl-LC-biotin Structure
Iodoacetyl-LC-biotin structure
Common Name Iodoacetyl-LC-biotin
CAS Number 93285-75-7 Molecular Weight 510.43300
Density 1.414g/cm3 Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C18H31IN4O3S Melting Point N/A
MSDS N/A Flash Point 433.8ºC

 Use of Iodoacetyl-LC-biotin


Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].

 Names

Name n-iodoacetyl-n-biotinylhexylenediamine
Synonym More Synonyms

 Iodoacetyl-LC-biotin Biological Activity

Description Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].
Related Catalog
In Vitro Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner[1]. IAB (50-200 µM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells[1].
References

[1]. Wong HL, et, al. Mitochondrial protein targets of thiol-reactive electrophiles. Chem Res Toxicol. 2008 Apr;21(4):796-804.

[2]. Davis KA, et, al. Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry. Nucleic Acids Res. 1998 Sep 1;26(17):3915-24.

 Chemical & Physical Properties

Density 1.414g/cm3
Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C18H31IN4O3S
Molecular Weight 510.43300
Flash Point 433.8ºC
Exact Mass 510.11600
PSA 124.63000
LogP 3.37940
Index of Refraction 1.559

 Safety Information

Hazard Codes Xi

 Synonyms

N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine
N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE
iodoacetyl-LC-biotin
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