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93285-75-7

93285-75-7 structure
93285-75-7 structure
  • Name: Iodoacetyl-LC-biotin
  • Chemical Name: n-iodoacetyl-n-biotinylhexylenediamine
  • CAS Number: 93285-75-7
  • Molecular Formula: C18H31IN4O3S
  • Molecular Weight: 510.43300
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2019-01-01 14:55:34
  • Modify Date: 2024-01-28 11:27:11
  • Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].

Name n-iodoacetyl-n-biotinylhexylenediamine
Synonyms N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine
N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE
iodoacetyl-LC-biotin
Description Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].
Related Catalog
In Vitro Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner[1]. IAB (50-200 µM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells[1].
References

[1]. Wong HL, et, al. Mitochondrial protein targets of thiol-reactive electrophiles. Chem Res Toxicol. 2008 Apr;21(4):796-804.

[2]. Davis KA, et, al. Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry. Nucleic Acids Res. 1998 Sep 1;26(17):3915-24.

Density 1.414g/cm3
Boiling Point 793.7ºC at 760 mmHg
Molecular Formula C18H31IN4O3S
Molecular Weight 510.43300
Flash Point 433.8ºC
Exact Mass 510.11600
PSA 124.63000
LogP 3.37940
Index of Refraction 1.559
Hazard Codes Xi