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2517899-65-7

2517899-65-7 structure
2517899-65-7 structure
  • Name: Iodoacetyl-PEG4-NHS ester
  • Chemical Name: Iodoacetyl-PEG4-NHS ester
  • CAS Number: 2517899-65-7
  • Molecular Formula: C17H27IN2O9
  • Molecular Weight: 530.31
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-16 09:14:09
  • Modify Date: 2024-01-08 17:59:50
  • Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Iodoacetyl-PEG4-NHS ester
Description Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H27IN2O9
Molecular Weight 530.31