DPNI-caged-GABA

Modify Date: 2025-08-26 17:39:16

Use of DPNI-caged-GABA

DPNI-GABA is a nitroindoline cage compound that inhibits GABA(A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].

Name	1-Butanone, 4-amino-1-[2,3-dihydro-7-nitro-4-[2-(phosphonooxy)-1-[(phosphonooxy)methyl]ethoxy]-1H-indol-1-yl]
Synonym	More Synonyms

Description	DPNI-GABA is a nitroindoline cage compound that inhibits GABA(A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. Trigo FF, et al. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J Neurosci Methods. 2009 Jul 30;181(2):159-69.

Density	1.676±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point	900.8±75.0 °C (760 mmHg)
Molecular Formula	C₁₅H₂₃N₃O₁₂P₂
Molecular Weight	499.30
Exact Mass	499.07600
PSA	254.52000
LogP	1.47730
InChIKey	QLCHBTSDKGMLRN-UHFFFAOYSA-N
SMILES	NCCCC(=O)N1CCc2c(OC(COP(=O)(O)O)COP(=O)(O)O)ccc([N+](=O)[O-])c21

DPNI-CAGED GABA

DPNI-caged-GABA

4-Amino-1-[2,3-dihydro-7-nitro-4-[2-(phosphonooxy)-1-[(phosphonooxy)methyl]ethoxy]-1H-indol-1-yl]-1-butanone

Bicifadine hydrochloride

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