DPNI-caged-GABA

Modify Date: 2024-01-24 16:32:05

DPNI-caged-GABA Structure
DPNI-caged-GABA structure
Common Name DPNI-caged-GABA
CAS Number 927866-58-8 Molecular Weight 499.30
Density 1.676±0.06 g/cm3 (20 °C, 760 mmHg) Boiling Point 900.8±75.0 °C (760 mmHg)
Molecular Formula C15H23N3O12P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DPNI-caged-GABA


DPNI-GABA is a nitroindoline cage compound that inhibits GABA(A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].

 Names

Name 1-Butanone, 4-amino-1-[2,3-dihydro-7-nitro-4-[2-(phosphonooxy)-1-[(phosphonooxy)methyl]ethoxy]-1H-indol-1-yl]
Synonym More Synonyms

 DPNI-caged-GABA Biological Activity

Description DPNI-GABA is a nitroindoline cage compound that inhibits GABA(A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].
Related Catalog
References

[1]. Trigo FF, et al. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J Neurosci Methods. 2009 Jul 30;181(2):159-69.  

 Chemical & Physical Properties

Density 1.676±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point 900.8±75.0 °C (760 mmHg)
Molecular Formula C15H23N3O12P2
Molecular Weight 499.30
Exact Mass 499.07600
PSA 254.52000
LogP 1.47730

 Synonyms

DPNI-CAGED GABA
DPNI-caged-GABA
4-Amino-1-[2,3-dihydro-7-nitro-4-[2-(phosphonooxy)-1-[(phosphonooxy)methyl]ethoxy]-1H-indol-1-yl]-1-butanone
Bicifadine hydrochloride