Butyrolactone I
Modify Date: 2025-08-21 11:43:27
Butyrolactone I structure
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Common Name | Butyrolactone I | ||
|---|---|---|---|---|
| CAS Number | 87414-49-1 | Molecular Weight | 424.44300 | |
| Density | 1.342g/cm3 | Boiling Point | 661.1ºC at 760 mmHg | |
| Molecular Formula | C24H24O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 228ºC | |
Use of Butyrolactone IButyrolactone I is an ATP-competitive inhibitor of CDK1 as a secondary metabolite from A. terreus[1]. Butyrolactone I has antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines[2]. |
| Name | [4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl (2R)-4-hydroxy-3-(4-hydroxyphenyl)-2-methyl-5-oxofuran-2-carboxylate |
|---|
| Description | Butyrolactone I is an ATP-competitive inhibitor of CDK1 as a secondary metabolite from A. terreus[1]. Butyrolactone I has antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines[2]. |
|---|---|
| Related Catalog | |
| Target |
CDK1 |
| References |
| Density | 1.342g/cm3 |
|---|---|
| Boiling Point | 661.1ºC at 760 mmHg |
| Molecular Formula | C24H24O7 |
| Molecular Weight | 424.44300 |
| Flash Point | 228ºC |
| Exact Mass | 424.15200 |
| PSA | 113.29000 |
| LogP | 3.58690 |
| Index of Refraction | 1.633 |
| InChIKey | NGOLMNWQNHWEKU-XMMPIXPASA-N |
| SMILES | COC(=O)C1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(O)=C1c1ccc(O)cc1 |