Butyrolactone 3 structure
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Common Name | Butyrolactone 3 | ||
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CAS Number | 778649-18-6 | Molecular Weight | 184.189 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 386.2±42.0 °C at 760 mmHg | |
Molecular Formula | C9H12O4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 158.5±21.4 °C |
Use of Butyrolactone 3Butyrolactone 3 is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM)[1] |
Name | (2S,3R)-4-methylidene-5-oxo-2-propyloxolane-3-carboxylic acid |
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Synonym | More Synonyms |
Description | Butyrolactone 3 is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM)[1] |
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Related Catalog | |
Target |
GCN5:100 μM (IC50) |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 386.2±42.0 °C at 760 mmHg |
Molecular Formula | C9H12O4 |
Molecular Weight | 184.189 |
Flash Point | 158.5±21.4 °C |
Exact Mass | 184.073563 |
PSA | 63.60000 |
LogP | 0.99 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.495 |
Storage condition | -20°C |
Butyrolactone 3 |
3-Furancarboxylic acid, tetrahydro-4-methylene-5-oxo-2-propyl-, (2S,3R)- |
(2S,3R)-4-Methylene-5-oxo-2-propyltetrahydro-3-furancarboxylic acid |