Flt-3 Inhibitor III
Modify Date: 2024-01-11 16:15:45
Flt-3 Inhibitor III structure
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Common Name | Flt-3 Inhibitor III | ||
|---|---|---|---|---|
| CAS Number | 852045-46-6 | Molecular Weight | 365.492 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 554.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C21H23N3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 288.9±32.9 °C | |
Use of Flt-3 Inhibitor IIIFlt-3 Inhibitor III is a potent and selective FLT3 kinase inhibitor with an 50 of 50 nM. Flt-3 Inhibitor III shows less active against other kinases. Flt-3 Inhibitor III has anticancer effects[1]. |
| Name | FLT3 Inhibitor III |
|---|---|
| Synonym | More Synonyms |
| Description | Flt-3 Inhibitor III is a potent and selective FLT3 kinase inhibitor with an 50 of 50 nM. Flt-3 Inhibitor III shows less active against other kinases. Flt-3 Inhibitor III has anticancer effects[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 50 nM (FLT3 kinase)[1] |
| In Vitro | Flt-3 Inhibitor III（化合物 4）也抑制 c-Kit、KDR、c-Abl、CDK1、c-Src 和 Tie-2，IC50 值分别为 0.26 µM、0.91 µM、1.2 µM、2.1 µM、2.8 µM 和 8.0 µM[1]。 Flt-3 Inhibitor III（化合物 4）阻断 BaF3-ITD、BaF3-D835/Y 和 MV4:11 细胞的增殖，IC50 值分别为 0.24 µM、0.76 µM 和 0.052 µM[1] 。 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 554.1±60.0 °C at 760 mmHg |
| Molecular Formula | C21H23N3OS |
| Molecular Weight | 365.492 |
| Flash Point | 288.9±32.9 °C |
| Exact Mass | 365.156189 |
| LogP | 4.48 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.640 |
| FLT3 Inhibitor III |
| 2-Thiazolamine, 5-phenyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]- |
| 5-Phenyl-N-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1,3-thiazol-2-amine |
| Flt-3 Inhibitor III |