IFN alpha-IFNAR-IN-1

Modify Date: 2024-01-06 19:13:23

IFN alpha-IFNAR-IN-1 structure	Common Name	IFN alpha-IFNAR-IN-1
	CAS Number	844882-93-5	Molecular Weight	279.399
	Density	1.2±0.1 g/cm3	Boiling Point	419.4±28.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₇NS	Melting Point	N/A
	MSDS	N/A	Flash Point	207.5±24.0 °C

Use of IFN alpha-IFNAR-IN-1

IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).IC50 value:Target: IFN alpha-IFNAR interaction inhibitorIFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α [1].

Name	IFN alpha-IFNAR-IN-1
Synonym	More Synonyms

Description	IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).IC50 value:Target: IFN alpha-IFNAR interaction inhibitorIFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α [1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> IFNAR Research Areas >> Inflammation/Immunology
References	[1]. Geppert T, et al. Immunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions. Angew Chem Int Ed Engl. 2012 Jan 2;51(1):258-61.

Density	1.2±0.1 g/cm3
Boiling Point	419.4±28.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₇NS
Molecular Weight	279.399
Flash Point	207.5±24.0 °C
Exact Mass	279.108185
LogP	4.98
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.680
Storage condition	2-8℃

N-Methyl-1-[2-(1-naphthylsulfanyl)phenyl]methanamine

Benzenemethanamine, N-methyl-2-(1-naphthalenylthio)-

DC Chemicals Limited
China
Product Name: IFNAR-IN-1
Price: $Inquiry/25mg $Inquiry/50mg $Inquiry/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: IFN alpha-IFNAR-IN-1
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

IFN alpha-IFNAR-IN-1 suppliers

Price: $108/5mg

Reference only. check more IFN alpha-IFNAR-IN-1 price

IFN alpha-IFNAR-IN-1

Use of IFN alpha-IFNAR-IN-1

Names

IFN alpha-IFNAR-IN-1 Biological Activity

Chemical & Physical Properties

Synonyms