IFN alpha-IFNAR-IN-1
Modify Date: 2025-09-01 11:31:58
IFN alpha-IFNAR-IN-1 structure
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Common Name | IFN alpha-IFNAR-IN-1 | ||
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| CAS Number | 844882-93-5 | Molecular Weight | 279.399 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 419.4±28.0 °C at 760 mmHg | |
| Molecular Formula | C18H17NS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 207.5±24.0 °C | |
Use of IFN alpha-IFNAR-IN-1IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).IC50 value:Target: IFN alpha-IFNAR interaction inhibitorIFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α [1]. |
| Name | IFN alpha-IFNAR-IN-1 |
|---|---|
| Synonym | More Synonyms |
| Description | IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM).IC50 value:Target: IFN alpha-IFNAR interaction inhibitorIFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α [1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 419.4±28.0 °C at 760 mmHg |
| Molecular Formula | C18H17NS |
| Molecular Weight | 279.399 |
| Flash Point | 207.5±24.0 °C |
| Exact Mass | 279.108185 |
| LogP | 4.98 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.680 |
| InChIKey | OHDXDNUPVVYWOV-UHFFFAOYSA-N |
| SMILES | CNCc1ccccc1Sc1cccc2ccccc12 |
| Storage condition | 2-8℃ |
| N-Methyl-1-[2-(1-naphthylsulfanyl)phenyl]methanamine |
| Benzenemethanamine, N-methyl-2-(1-naphthalenylthio)- |