1613480-70-8

1613480-70-8 structure

Name: Cholesterol 24-hydroxylase-IN-1
Chemical Name: Cholesterol 24-hydroxylase-IN-1
CAS Number: 1613480-70-8
Molecular Formula: C₁₇H₂₃N₅O
Molecular Weight: 313.40
Create Date: 2022-06-18 22:24:08
Modify Date: 2025-08-25 10:30:44
Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].

Name	Cholesterol 24-hydroxylase-IN-1

Description	Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease
References	[1]. Kajita Y, et al. Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. J Med Chem. 2022;65(4):3343-3358.

Molecular Formula	C₁₇H₂₃N₅O
Molecular Weight	313.40