448947-81-7
448947-81-7 structure
- Name: Yoda 1
- Chemical Name: GlyT2-IN-1
- CAS Number: 448947-81-7
- Molecular Formula: C13H8Cl2N4S2
- Molecular Weight: 355.265
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel GlyT
- Create Date: 2018-01-26 21:29:51
- Modify Date: 2025-08-20 15:25:07
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GlyT2-IN-1 is a glycine transporters GLYT2 inhibitor.Target: GLYT2The Glycine Transporter GlyT2 Controls the Dynamics of Synaptic Vesicle Refilling in Inhibitory Spinal Cord Neurons. GlyT2-IN-1 is a novel agonist of the mechanotransduction channel Piezo1, eliciting Ca2+ flux in Piezo1- but not vector-transfected cells.
| Name | GlyT2-IN-1 |
|---|---|
| Synonyms |
2-{5-[(2,6-Dichlorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}pyrazine
2-[(2,6-dichlorobenzyl)thio]-5-pyrazin-2-yl-1,3,4-thiadiazole MFCD00833175 Pyrazine, 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]- |
| Description | GlyT2-IN-1 is a glycine transporters GLYT2 inhibitor.Target: GLYT2The Glycine Transporter GlyT2 Controls the Dynamics of Synaptic Vesicle Refilling in Inhibitory Spinal Cord Neurons. GlyT2-IN-1 is a novel agonist of the mechanotransduction channel Piezo1, eliciting Ca2+ flux in Piezo1- but not vector-transfected cells. |
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| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 538.4±60.0 °C at 760 mmHg |
| Molecular Formula | C13H8Cl2N4S2 |
| Molecular Weight | 355.265 |
| Flash Point | 279.4±32.9 °C |
| Exact Mass | 353.956757 |
| LogP | 4.89 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.714 |