N-Benzhydrylpiperazine

Modify Date: 2025-08-24 17:35:40

N-Benzhydrylpiperazine structure	Common Name	N-Benzhydrylpiperazine
	CAS Number	841-77-0	Molecular Weight	252.354
	Density	1.1±0.1 g/cm3	Boiling Point	365.1±32.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₀N₂	Melting Point	90-93 °C
	MSDS	Chinese USA	Flash Point	140.5±16.1 °C
	Symbol	GHS07	Signal Word	Warning

Name	Benzhydrylpiperazine
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	365.1±32.0 °C at 760 mmHg
Melting Point	90-93 °C
Molecular Formula	C₁₇H₂₀N₂
Molecular Weight	252.354
Flash Point	140.5±16.1 °C
Exact Mass	252.162643
PSA	15.27000
LogP	2.85
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.584
Water Solubility	0.45 g/L (20 ºC)

N-Benzhydrylpiperazine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL6465000

CHEMICAL NAME :: Piperazine, 1-(diphenylmethyl)-

CAS REGISTRY NUMBER :: 841-77-0

BEILSTEIN REFERENCE NO. :: 0222773

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C17-H20-N2

MOLECULAR WEIGHT :: 252.39

WISWESSER LINE NOTATION :: T6M DNTJ DYR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),28,1997

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),28,1997

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 38 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 31,453,1972

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TL6465000
Packaging Group	I; II; III
HS Code	2942000000

Precursor 10
CAS#:142-64-3 piperazine dihy... CAS#:90-99-3 benzhydryl chloride CAS#:110-85-0 Piperazine CAS#:102552-76-1 1-benzhydryl-4-...
CAS#:776-74-9 Bromodiphenylmethane CAS#:119-61-9 Benzophenone CAS#:91-01-0 Benzhydrol CAS#:7755-92-2 formylpiperazine
CAS#:100-52-7 Benzaldehyde CAS#:82-92-8 Cyclizine
DownStream 10
CAS#:104690-88-2 1-benzhydryl-4-... CAS#:110629-35-1 N-[2-(4-benzhyd... CAS#:110629-32-8 4-[2-(4-benzhyd... CAS#:10527-64-7 2-(4-benzhydryl...
CAS#:104690-91-7 1-[bis(4-fluoro... CAS#:3733-63-9 Decloxizine CAS#:60607-34-3 Oxatomide CAS#:41332-24-5 NP118809
CAS#:89226-50-6 Manidipine CAS#:84625-59-2 1-benzhydryl-4-...

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Quantification of cyclizine and norcyclizine in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(9-10) , 605-9, (2011)

A rapid and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay was developed and validated for quantification of cyclizine and its main metabolite norcyclizine in human plasma. Sam...

Oxidative metabolism of cinnarizine in rat liver microsomes.

Biochem. Pharmacol. 44(7) , 1471-4, (1992)

The oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] to 1-(diphenylmethyl)piperazine (M-1), 1-(diphenylmethyl)-4-[3-(4'-hydroxyphenyl)-2-propenyl]pipera...

The reactions of polyhalogenated-2-nitro-1, 3-butadiene with alkylthio, thiomorpholine and piperazine derivatives. Ibis C and Deniz NG.

Indian J. Chem. B 47(9) , 1407, (2008)

Piperazine, 1-(diphenylmethyl)-

EINECS 212-667-7

N-Benzhydrylpiperazine

1-benzhydrylpiperazine

MFCD00038379

Piperazine, 1- (diphenylmethyl)-

1-(Diphenylmethyl)piperazine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: N-Benzhydrylpiperazine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: N-Benzhydrylpiperazine
Price: ￥188.0/5g ￥758.0/25g
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(Diphenylmethyl)piperazine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Benzhydrylpiperazine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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N-Benzhydrylpiperazine

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