Cyclizine

Modify Date: 2025-08-23 12:16:34

Cyclizine structure	Common Name	Cyclizine
	CAS Number	82-92-8	Molecular Weight	266.38100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₂N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	cyclizine
Synonym	More Synonyms

Molecular Formula	C₁₈H₂₂N₂
Molecular Weight	266.38100
Exact Mass	266.17800
PSA	6.48000
LogP	2.89920

Cyclizine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL6475000

CHEMICAL NAME :: Piperazine, 1-(diphenylmethyl)-4-methyl-

CAS REGISTRY NUMBER :: 82-92-8

BEILSTEIN REFERENCE NO. :: 0230441

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H22-N2

MOLECULAR WEIGHT :: 266.42

WISWESSER LINE NOTATION :: T6N DNTJ AYR&R& D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 126 mg/kg/6W-I

TOXIC EFFECTS :: Blood - agranulocytosis

REFERENCE :: BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 292,174,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 147 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,218,1972 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 450 mg/kg

SEX/DURATION :: female 10-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,323,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 450 mg/kg

SEX/DURATION :: female 10-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - homeostasis Reproductive - Effects on Newborn - stillbirth

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 109,323,1970 *** REVIEWS *** TOXICOLOGY REVIEW ADVPA3 Advances in Pharmacology. (New York, NY) V.1-6, 1962-68. For publisher information, see AVPCAQ. Volume(issue)/page/year: 4,263,1966

Hazard Codes	T+
HS Code	2933599090

methylpiperazine

CAS#:109-01-3

benzhydryl chloride

CAS#:90-99-3

~30%

Cyclizine

CAS#:82-92-8

Literature: US2009/176792 A1, ; Page/Page column 26 ;

N-Methyldiethan...

CAS#:105-59-9

diphenylmethylamine

CAS#:91-00-9

~18%

Cyclizine

CAS#:82-92-8

Literature: Journal of Organic Chemistry, , vol. 50, # 9 p. 1365 - 1370

Piperazine

CAS#:110-85-0

Bromodiphenylmethane

CAS#:776-74-9

methyl iodide

CAS#:74-88-4

~43%

Cyclizine

CAS#:82-92-8

Literature: Journal of the American Chemical Society, , vol. 119, # 14 p. 3288 - 3295

1-benzhydryl-4-...

CAS#:102552-76-1

Cyclizine

CAS#:82-92-8

Literature: BE539693 , ;

Precursor 8
CAS#:109-01-3 methylpiperazine CAS#:90-99-3 benzhydryl chloride CAS#:105-59-9 N-Methyldiethan... CAS#:91-00-9 diphenylmethylamine
CAS#:110-85-0 Piperazine CAS#:776-74-9 Bromodiphenylmethane CAS#:74-88-4 methyl iodide CAS#:102552-76-1 1-benzhydryl-4-...
DownStream 2
CAS#:841-77-0 N-Benzhydrylpip... CAS#:139329-22-9 ethyl 5-(4-benz...

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Ciclizina

Marzine

N-benzhydryl-N'-methylpiperazine

Valoid

Bw 47-83

Marazine

1-Benzhydryl-4-methyl-piperazin

Emoquil

Nautazine

Marezine

Wellcome

CYCLIZINE HCL

1-diphenylmethyl-4-methylpiperazine

1-benzhydryl-4-methyl-piperazine

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclizine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Cyclizine
Price: $500.0/100mg $850.0/250mg $1700.0/1g
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Cyclizine
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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Cyclizine

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.