Ym-244769
Modify Date: 2025-08-25 19:27:55
Ym-244769 structure
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Common Name | Ym-244769 | ||
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| CAS Number | 838819-70-8 | Molecular Weight | 443.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H22FN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ym-244769YM-244769 is a potent NCX (Na+/Ca2+ exchange) inhibitor that preferentially inhibits NCX3, with an IC50 of 18 nM. YM-244769 efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage[1]. |
| Name | YM-244769 |
|---|
| Description | YM-244769 is a potent NCX (Na+/Ca2+ exchange) inhibitor that preferentially inhibits NCX3, with an IC50 of 18 nM. YM-244769 efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage[1]. |
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| Related Catalog | |
| Target |
IC50: 18 nM (NCX3)[1] |
| In Vitro | YM-244769 preferentially inhibits intracellular Na+-dependent 45Ca2+ uptake via NCX3; the inhibition is 3.8- to 5.3-fold greater than for the uptake via NCX1 or NCX2[1]. |
| References |
| Molecular Formula | C26H22FN3O3 |
|---|---|
| Molecular Weight | 443.47 |