DC Chemicals Limited
China
Product Name: YM26734
Price: ￥Inquiry/100mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

144337-18-8

144337-18-8 structure

144337-18-8 structure

Name: YM 26734
Chemical Name: 1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one
CAS Number: 144337-18-8
Molecular Formula: C₄₅H₆₂O₈
Molecular Weight: 730.96900
Create Date: 2017-01-29 05:06:52
Modify Date: 2024-01-13 12:35:03
YM-26734 is a competitive inhibitor of secretory phospholipase A2 (PLA2) that exhibits a broad inhibitory profile to several PLA2s[1].

Name	1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one
Synonyms	YM26734

Description	YM-26734 is a competitive inhibitor of secretory phospholipase A2 (PLA2) that exhibits a broad inhibitory profile to several PLA2s[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Inflammation/Immunology
Target	sPLA2
References	[1]. Miyake A, et al. Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2. Br J Pharmacol. 1993 Sep;110(1):447-53.

Density	1.14g/cm3
Boiling Point	797.832ºC at 760 mmHg
Molecular Formula	C₄₅H₆₂O₈
Molecular Weight	730.96900
Flash Point	228.539ºC
Exact Mass	730.44400
PSA	144.52000
LogP	12.07750
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.572

144337-17-7 structure

144337-17-7

~48%

144337-18-8 structure

144337-18-8

Literature: Oslund, Rob C.; Cermak, Nathan; Verlinde, Christophe L.M.J.; Gelb, Michael H. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5415 - 5419

Precursor 1
144337-17-7
DownStream 0