Shanghai Nianxing Industrial Co., Ltd
China
Product Name: YM-08
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Purity: 99.0%
Stocking Period: 10 Day
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812647-88-4

812647-88-4 structure

812647-88-4 structure

Name: 3-Ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-2-(2-pyridinylmethylene)-4-thiazolidinone
Chemical Name: YM-08
CAS Number: 812647-88-4
Molecular Formula: C₁₉H₁₇N₃OS₂
Molecular Weight: 367.49
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2022-03-27 08:31:15
Modify Date: 2025-09-02 13:37:33
YM-08 (Compounds 7a) is a brain-penetrant inhibitors of SIRT2,with the IC50 of 19.9 μM. YM-08 also is inhibitor of Hsp70[1].

Name	YM-08
Synonyms	(2Z,5E)-3-Ethyl-5-(3-methyl-1,3-benzothiazol-2-ylidene)-2-(pyridin-2-ylmethylidene)-1,3-thiazolidin-4-one

Description	YM-08 (Compounds 7a) is a brain-penetrant inhibitors of SIRT2,with the IC50 of 19.9 μM. YM-08 also is inhibitor of Hsp70[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Signaling Pathways >> Cell Cycle/DNA Damage >> HSP Research Areas >> Neurological Disease
Target	HSP70
References	[1]. Abbotto E, et al. Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays. Pharmaceuticals (Basel). 2023;16(9):1316. Published 2023 Sep 18.

Molecular Formula	C₁₉H₁₇N₃OS₂
Molecular Weight	367.49
Water Solubility	Soluble in DMSO

RIDADR	NONH for all modes of transport

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