1,8-Naphthalic anhydride

Modify Date: 2024-01-02 20:56:32

1,8-Naphthalic anhydride Structure
1,8-Naphthalic anhydride structure
Common Name 1,8-Naphthalic anhydride
CAS Number 81-84-5 Molecular Weight 198.174
Density 1.5±0.1 g/cm3 Boiling Point 407.5±14.0 °C at 760 mmHg
Molecular Formula C12H6O3 Melting Point 269 °C
MSDS Chinese USA Flash Point 206.8±17.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name naphthalic anhydride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 407.5±14.0 °C at 760 mmHg
Melting Point 269 °C
Molecular Formula C12H6O3
Molecular Weight 198.174
Flash Point 206.8±17.3 °C
Exact Mass 198.031693
PSA 43.37000
LogP 1.75
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.712
Water Solubility decomposes

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK5350000
CHEMICAL NAME :
1,8-Naphthalic anhydride
CAS REGISTRY NUMBER :
81-84-5
BEILSTEIN REFERENCE NO. :
0153190
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C12-H6-O3
MOLECULAR WEIGHT :
198.18
WISWESSER LINE NOTATION :
T666 1A M CVOVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
12340 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C253,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533580
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533580
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533580
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2025 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,590,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
4100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,590,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>6810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 8,590,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS QK5350000
Hazard Class 4.1
HS Code 29173980

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles11

More Articles
1,8-Naphthalic anhydride antidote enhances the toxic effects of captan and thiram fungicides on Azospirillum brasilense cells.

Res. Microbiol. 142(9) , 1005-12, (1991)

The effects of ten fungicides, six herbicides and four insecticides on the nitrogen-fixing bacterium Azospirillum brasilense were examined. The fungicides captan and thiram were the most toxic among t...

Sensitive enantiomeric separation of aliphatic and aromatic amines using aromatic anhydrides as nonchiral derivatizing agents.

J. Chromatogr. A. 666 , 485-491, (1994)

New pre-column derivatizing reagents: phthalic anhydride, 3-nitrophthalic anhydride, diphenic anhydride, 1,8-naphthalic anhydride and diphenylmaleic anhydride have been developed for resolving chiral ...

Differential induction of cytochrome P450-mediated triasulfuron metabolism by naphthalic anhydride and triasulfuron.

Plant Physiol. 109(4) , 1483-90, (1995)

Cytochrome P450 monooxygenases play paramount roles in the detoxification of herbicides as well as in the synthesis of lignins, flavonoids, and phenolic acids. Biochemical analysis of triasulfuron met...

 Synonyms

1H,3H-Benzo[de]isochromene-1,3-dione
1,8-naphthalene dicarboxylic anhydride
1H,3H-naphtho [1,8-cd]pyran-1,3-dione
Protect
naphthalic
1,8-naphthalic anhydride
MFCD00006925
NAPHTHALIC ANHYDRIDE
PROTECT(R)
naphthalene-1,8-dicarboxylic acid anhydride
1H,3H-Naphtho[1,8-cd]pyran-1,3-dione
1,8-Naphthalic
EINECS 201-380-2
1,8-Naphthalenedicarboxylic acid anhydride
pakarli
naphthalene-1,8-dicarboxylic anhydride
1,8-dinaphthoic anhydride
1H,3H-Naphtho(1,8-cd)pyran-1,3-dione (9CI)
1,8-Naphthalic anhyd
protect(agrochemical)
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