Alrestatin

Modify Date: 2024-01-04 09:55:02

Alrestatin Structure
Alrestatin structure
 Common Name Alrestatin
CAS Number 51411-04-2 Molecular Weight 168.042
Density 1.7±0.1 g/cm3 Boiling Point 359.1±44.0 °C at 760 mmHg
Molecular Formula C14H9NO4 Melting Point N/A
MSDS N/A Flash Point 171.0±28.4 °C

 Use of Alrestatin


Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.

 Names

Name 2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetic acid
Synonym More Synonyms

 Alrestatin Biological Activity

Description Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
Related Catalog

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 359.1±44.0 °C at 760 mmHg
Molecular Formula C14H9NO4
Molecular Weight 168.042
Flash Point 171.0±28.4 °C
Exact Mass 167.982376
PSA 76.37000
LogP -2.47
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.480
Storage condition -20℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DE4080500
CHEMICAL NAME :
1H-Benz(de)isoquinoline-2(3H)-acetic acid, 1,3-dioxo-
CAS REGISTRY NUMBER :
51411-04-2
BEILSTEIN REFERENCE NO. :
0244370
LAST UPDATED :
199703
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H9-N-O4
MOLECULAR WEIGHT :
255.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4405625
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1380 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4118495
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4118495

 Safety Information

HS Code 2933990090

 Synthetic Route

1,8-Naphthalic anhydride structure

1,8-Naphthalic ...

CAS#:81-84-5
Glycine structure

Glycine

CAS#:56-40-6

~96%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Donkor, Isaac O.; Abdel-Ghany, Yasser S.; Kador, Peter F.; Mizoguchi, Tadashi; Bartoszko-Malik, Anita; Miller, Duane D. European Journal of Medicinal Chemistry, 1998 , vol. 33, # 1 p. 15 - 22
N-(carboethoxymethyl)-1,8-naphthalimide structure

N-(carboethoxym...

CAS#:78052-77-4

~99%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Takahashi, Yasutake; Miyashi, Tsutomu; Yoon, Ung Chan; Oh, Sun Wha; Mancheno, Maria; Su, Zhuoyi; Falvey, Daniel F.; Mariano, Patrick S. Journal of the American Chemical Society, 1999 , vol. 121, # 16 p. 3926 - 3932
tert-butyl 2-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetate structure

tert-butyl 2-(1...

CAS#:476359-53-2

~98%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Ikeda, Hisafumi; Nakamura, Yushin; Saito, Isao Tetrahedron Letters, 2002 , vol. 43, # 32 p. 5525 - 5528
methyl (1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)acetate structure

methyl (1,3-dio...

CAS#:135980-44-8

~%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Avino, Anna; Navarro, Isabel; Farrera-Sinfreu, Josep; Royo, Miriam; Aymami, Juan; Delgado, Antonio; Llebaria, Amadeu; Albericio, Fernando; Eritja, Ramon Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 7 p. 2306 - 2310
1,8-Naphthalimide structure

1,8-Naphthalimide

CAS#:81-83-4

~%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Takahashi, Yasutake; Miyashi, Tsutomu; Yoon, Ung Chan; Oh, Sun Wha; Mancheno, Maria; Su, Zhuoyi; Falvey, Daniel F.; Mariano, Patrick S. Journal of the American Chemical Society, 1999 , vol. 121, # 16 p. 3926 - 3932
1,8-Naphthalic anhydride structure

1,8-Naphthalic ...

CAS#:81-84-5

~%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Stephen Journal of the Chemical Society, 1931 , p. 871,872
acetic acid structure

acetic acid

CAS#:64-19-7

~%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Fierz-David; Rossi Helvetica Chimica Acta, 1938 , vol. 21, p. 1466,1479, 1480
N-(cyanomethyl)-1,8-naphthalimide structure

N-(cyanomethyl)...

CAS#:353262-66-5

~%

Alrestatin Structure

Alrestatin

CAS#:51411-04-2
Literature: Stephen Journal of the Chemical Society, 1931 , p. 871,872

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Alrestatine
2,3-Dioxopropyl dihydrogen phosphate
Propanal, 2-oxo-3-(phosphonooxy)-
alrestatin
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Alrestatin
  • Price: $400.0/100mg $750.0/250mg $1500.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

Get all suppliers and price by the below link:

Alrestatin suppliers

Price: $106/10mM*1mLinDMSO

Reference only. check more Alrestatin price

Related Compounds: More...
ALRESTATIN SODIUM
51876-97-2
Chemsrc provides Alrestatin(CAS#:51411-04-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Alrestatin are included as well.>> amp version: Alrestatin

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved