|Common Name||Glycolic acid|
|CAS Number||79-14-1||Molecular Weight||76.051|
|Density||1.4±0.1 g/cm3||Boiling Point||265.6±13.0 °C at 760 mmHg|
|Molecular Formula||C2H4O3||Melting Point||75-80 °C(lit.)|
|MSDS||Chinese USA||Flash Point||128.7±16.3 °C|
Use of Glycolic acid
Glycolic Acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
|Description||Glycolic Acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.|
Human Endogenous Metabolite
|In Vitro||Different concentrations of Glycolic Acid (GA) or LA (300 and 500 mg/mL) are tested on the growth of mouse and human melanoma cells. Both types of cells grow well, even in the presence of 300 mg/mL of each chemical for 5 days. However, 500 mg/mL Glycolic Acid inhibits the cell growth of mouse melanoma cells (41%) and humanmelanoma cells (27%), and 500 mg/mL of LA inhibits the growth of mouse melanoma cells (36%).|
10 mM in DMSO
|Cell Assay||HM3KO pigmented human melanoma cells and B16 mouse melanoma cells are cultured in Dulbecco’s modified Eagles medium supplemented with 10%fetal calf serum and appropriate amounts of antibiotics and fungizone were dissolved at a concentration of 100mg/mL in distilled water. These chemicals (e.g., Glycolic Acid ) are added to the cell cultures at final concentrations of 300 or 500 mg/mL every 2 days for 5 days.|
|Shipping||Room temperature in continental US; may vary elsewhere|
|Related Molecules||3-Methyladenine | Hydrocortisone | Acetylcysteine | Tretinoin | Melatonine | Prostaglandin E2 | Nicotinamide | Adenosine triphosphate | 4-Acetamidophenol | Prostaglandin E1 | Dehydroepiandrosterone | Corticosterone | Progesterone | Docosahexaenoic Acid | NAD+|
*The above documents are provided by Medchemexpress and are for scientific research only.
|Boiling Point||265.6±13.0 °C at 760 mmHg|
|Melting Point||75-80 °C(lit.)|
|Flash Point||128.7±16.3 °C|
|Vapour Pressure||0.0±1.2 mmHg at 25°C|
|Index of Refraction||1.450|
|Stability||Stable. Incompatible with bases, oxidizing agents and reducing agents.|
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
|Precautionary Statements||P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338|
|Personal Protective Equipment||Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges|
|RIDADR||UN 3265 8/PG 3|
|Summary||2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%|
Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.
AAPS J. 17(1) , 256-67, (2015)
Carbohydrate functionalization of nanoparticles allows for targeting of C-type lectin receptors. This family of pattern recognition receptors expressed on innate immune cells, such as macrophages and ...
Physiology and pathophysiology of organic acids in cerebrospinal fluid.
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993)
Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo...
HMDB: a knowledgebase for the human metabolome.
Nucleic Acids Res. 37(Database issue) , D603-10, (2009)
The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...