M4 mAChR agonist-1

Modify Date: 2024-01-08 20:01:12

M4 mAChR agonist-1 Structure
M4 mAChR agonist-1 structure
 Common Name M4 mAChR agonist-1
CAS Number 785705-53-5 Molecular Weight 290.38
Density N/A Boiling Point N/A
Molecular Formula C14H18N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of M4 mAChR agonist-1


M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].

 Names

Name M4 mAChR agonist-1

 M4 mAChR agonist-1 Biological Activity

Description M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].
Related Catalog
Target

EC50: >10 μM (human M4)[1]

References

[1]. Wood MR, et al. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2016;26(13):3029-3033.

 Chemical & Physical Properties

Molecular Formula C14H18N4OS
Molecular Weight 290.38
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