M4 mAChR agonist-1

Modify Date: 2024-01-08 20:01:12

Use of M4 mAChR agonist-1

M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].

Name	M4 mAChR agonist-1

Description	M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
Target	EC50: >10 μM (human M4)[1]
References	[1]. Wood MR, et al. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2016;26(13):3029-3033.

Molecular Formula	C₁₄H₁₈N₄OS
Molecular Weight	290.38