diABZI STING agonist-1 (Tautomerism)

Modify Date: 2024-01-06 18:33:20

diABZI STING agonist-1 (Tautomerism) structure	Common Name	diABZI STING agonist-1 (Tautomerism)
	CAS Number	2138498-18-5	Molecular Weight	849.94
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₅₁N₁₃O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of diABZI STING agonist-1 (Tautomerism)

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

Name	diABZI STING agonist-1 Tautomerism

Description	diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> STING Research Areas >> Inflammation/Immunology
Target	EC50: 130 nM (human STNG in PBMCs) [1].
In Vitro	diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
In Vivo	diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, diABZI STING agonist-1 (compound 3) demonstrates high selectivity against more than 350 kinases tested[1].
References	[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

Molecular Formula	C₄₂H₅₁N₁₃O₇
Molecular Weight	849.94
Storage condition	-20°C

Hazard Codes	Xn