PPARδ/γ agonist 1

Modify Date: 2024-01-15 07:19:15

PPARδ/γ agonist 1 structure	Common Name	PPARδ/γ agonist 1
	CAS Number	1257641-15-8	Molecular Weight	421.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PPARδ/γ agonist 1

DB-959 (T3D-959 (free base)) is a potent dual PPAR delta/gamma inhibitor. DB-959 can be used for Alzheimer’s disease research[1].

Name	PPARδ/γ agonist 1

Description	DB-959 (T3D-959 (free base)) is a potent dual PPAR delta/gamma inhibitor. DB-959 can be used for Alzheimer’s disease research[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Neurological Disease
In Vivo	DB-959 (T3D-959 (free base)) (1 mg/kg; i.g.; daily, for 16 days; STZ-mediated Long Evans rats) restores STZ-mediated impairments of motor function[1]. Animal Model: STZ-mediated Long Evans rats[1] Dosage: 1 mg/kg Administration: Oral gavage; daily, for 16 days Result: Improved performance in the STZ-mediated rats and had neuroprotective for both granule and Purkinje cells.
References	[1]. Tong M, et, al. T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease. J Alzheimers Dis. 2016;51(1):123-38.

Molecular Formula	C₂₅H₂₇NO₅
Molecular Weight	421.49