(1S)-(-)-Alpha-Pinene

Modify Date: 2024-01-04 21:13:29

(1S)-(-)-Alpha-Pinene Structure
(1S)-(-)-Alpha-Pinene structure
Common Name (1S)-(-)-Alpha-Pinene
CAS Number 7785-26-4 Molecular Weight 136.234
Density 0.9±0.1 g/cm3 Boiling Point 157.9±7.0 °C at 760 mmHg
Molecular Formula C10H16 Melting Point -64ºC
MSDS Chinese USA Flash Point 32.2±0.0 °C
Symbol GHS02 GHS07 GHS09
GHS02, GHS07, GHS09
Signal Word Warning

 Use of (1S)-(-)-Alpha-Pinene


(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site[1].

 Names

Name (-)-α-pinene
Synonym More Synonyms

 (1S)-(-)-Alpha-Pinene Biological Activity

Description (-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site[1].
Related Catalog
In Vitro (-)-α-pinene enhances the quantity of non-rapid eye movement sleep (NREMS) without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial modulator of GABAA-BZD receptors and directly binding to the BZD binding site of GABAA receptor[1].
References

[1]. Yang H, et al. α-Pinene, a Major Constituent of Pine Tree Oils, Enhances Non-Rapid Eye Movement Sleep in Micethrough GABAA-benzodiazepine Receptors.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 157.9±7.0 °C at 760 mmHg
Melting Point -64ºC
Molecular Formula C10H16
Molecular Weight 136.234
Flash Point 32.2±0.0 °C
Exact Mass 136.125198
LogP 4.37
Vapour Pressure 3.5±0.1 mmHg at 25°C
Index of Refraction 1.479
Storage condition 2~8°C

 Safety Information

Symbol GHS02 GHS07 GHS09
GHS02, GHS07, GHS09
Signal Word Warning
Hazard Statements H226-H315-H317-H319-H335-H410
Precautionary Statements P261-P273-P280-P305 + P351 + P338-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;N:Dangerousfortheenvironment;
Risk Phrases R10;R36/37/38;R43;R50
Safety Phrases S16-S26-S36/37-S61
RIDADR UN 2052/2368
WGK Germany 1
Packaging Group III
Hazard Class 3.0
HS Code 29021910

 Synthetic Route

 Customs

HS Code 2902199090
Summary 2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

 Synonyms

(1S,5S)-2,6,6-Trimethyl-bicyclo[3.1.1]hept-2-ene
(1S,5S)-2,6,6-Trimethylbicyclo[3.1.1]hept-2-ene
(1S,5S)-Pin-2-ene
Bicyclo[3.1.1]hept-2-ene, 2,6,6-trimethyl-, (1S,5S)-
MFCD00064145
(1S)-(-)-alpha-Pinene
(1S)-(-)-α-Pinene
α-Pinene
EINECS 232-077-3
L46 A EUTJ A1 A1 D1 &&(-)-α or (1S,5S)- Form
(-)-alpha-pinene
Pinene
(1S,5S)-α-Pinene
(1S,5S)-4,6,6-trimethylbicyclo[3.1.1]hept-3-ene