ethyl ethoxalylpropionate

Modify Date: 2025-08-23 17:19:02

ethyl ethoxalylpropionate Structure
ethyl ethoxalylpropionate structure
Common Name ethyl ethoxalylpropionate
CAS Number 759-65-9 Molecular Weight 202.204
Density 1.1±0.1 g/cm3 Boiling Point 249.9±0.0 °C at 760 mmHg
Molecular Formula C9H14O5 Melting Point N/A
MSDS Chinese USA Flash Point 111.3±22.7 °C

 Use of ethyl ethoxalylpropionate


Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release[1].

 Names

Name diethyl 2-methyl-3-oxosuccinate
Synonym More Synonyms

 ethyl ethoxalylpropionate Biological Activity

Description Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release[1].
Related Catalog
References

[1]. Inès Msolli, et al. Synthesis of nanoparticles based on PDMMLA derivative copolymers and study of warfarin encapsulation and controlled release. RSC Advances. Issue 11, 2017.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 249.9±0.0 °C at 760 mmHg
Molecular Formula C9H14O5
Molecular Weight 202.204
Flash Point 111.3±22.7 °C
Exact Mass 202.084122
PSA 69.67000
LogP 1.03
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.434

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Safety Phrases S23-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918300090

 Synthetic Route

~67%

ethyl ethoxalylpropionate Structure

ethyl ethoxalyl...

CAS#:759-65-9

Literature: Shirude, Pravin S.; Shandil, Radha; Sadler, Claire; Naik, Maruti; Hosagrahara, Vinayak; Hameed, Shahul; Shinde, Vikas; Bathula, Chandramohan; Humnabadkar, Vaishali; Kumar, Naveen; Reddy, Jitendar; Panduga, Vijender; Sharma, Sreevalli; Ambady, Anisha; Hegde, Naina; Whiteaker, James; McLaughlin, Robert E.; Gardner, Humphrey; Madhavapeddi, Prashanti; Ramachandran, Vasanthi; Kaur, Parvinder; Narayan, Ashwini; Guptha, Supreeth; Awasthy, Disha; Narayan, Chandan; Mahadevaswamy, Jyothi; Vishwas; Ahuja, Vijaykamal; Srivastava, Abhishek; Prabhakar, Kr; Bharath, Sowmya; Kale, Ramesh; Ramaiah, Manjunatha; Choudhury, Nilanjana Roy; Sambandamurthy, Vasan K.; Solapure, Suresh; Iyer, Pravin S.; Narayanan, Shridhar; Chatterji, Monalisa Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9701 - 9708

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ethyl ethoxalylpropionate Structure

ethyl ethoxalyl...

CAS#:759-65-9

Literature: Justus Liebigs Annalen der Chemie, , vol. 246, p. 329

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Detail
Literature: Journal of the Chemical Society, , vol. 125, p. 313 Justus Liebigs Annalen der Chemie, , vol. 246, p. 329 Organic Syntheses, , vol. 17, p. 54

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Detail
Literature: Journal of the Chemical Society, , vol. 125, p. 313 Justus Liebigs Annalen der Chemie, , vol. 246, p. 329 Organic Syntheses, , vol. 17, p. 54

~%

ethyl ethoxalylpropionate Structure

ethyl ethoxalyl...

CAS#:759-65-9

Detail
Literature: Journal of the Chemical Society, , p. 1079,1086

 Customs

HS Code 2918300090
Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles3

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Bioorg. Med. Chem. Lett. 18 , 205-209, (2008)

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Synthesis of New Homopolyester and Copolyesters by Anionic Ring-opening Polymerization of a, a', ß-Trisubstituted ß-Lactones. Barbaud C, et al.

Macromol. Chem. Phys. 205(2) , 199-207, (2004)

 Synonyms

Propanoic acid, 2-(ethoxyoxoacetyl)-, ethyl ester
Ethyl α-ethoxalylpropionate
Diethyl 2-methyl-3-oxosuccinate
Diethyl Methyloxalacetate
Butanedioic acid, 2-methyl-3-oxo-, diethyl ester
diethyl 2-methyl-3-oxobutanedioate
MFCD00009163
Butanedioic acid, methyloxo-, diethyl ester
diethyl 3-methyl-2-oxobutanedioate
ethyl ethoxalylpropionate
EINECS 227-750-3
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