SKF 81297 hydrobromide

Modify Date: 2025-08-25 13:40:20

Use of SKF 81297 hydrobromide

SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist[1].

Name	(R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide
Synonym	More Synonyms

Description	SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D1 Receptor
In Vivo	SKF 81297 hydrobromide (0.05-0.3 mg/kg，肌注，一次) 刺激 MPTP 损伤猴子的运动行为[1]。 Animal Model: Four male rhesus monkeys (Macaca mulatta, 7.0-11.3 kg)[1] Dosage: 0.05-0.3 mg/kg Administration: Injected intramuscularly (i.m.), once Result: Significantly increased rotational behaviour and right-sided hand use in unilateral MPTP-lesioned rhesus monkeys.
References	[1]. Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235(1):143-7. [2]. Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.

WGK Germany	3
HS Code	2933990090

Precursor 9
CAS#:67287-38-1 6-chloro-7,8-di... CAS#:621-59-0 Isovanillin CAS#:67287-37-0 N-(2-Hydroxy-2-... CAS#:93983-14-3 2-chloro-1-(chl...
CAS#:5417-17-4 2-Chloro-3,4-di... CAS#:37687-57-3 2-Chloro-3-hydr... CAS#:67287-36-9 2-(2-Chloro-3,4... CAS#:7537-07-7 (2-chloro-3,4-d...
CAS#:93983-13-2 (2-Chloro-3,4-d...
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-, (1R)-, hydrobromide (1:1)

R-(+)-SKF-81297 hydrobromide

(±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide (1:1)

6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

(1R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide (1:1)

Metastin (human)

(R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-, hydrobromide (1:1)

(+/-)-6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine hydrobromide

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥3000/5 mg