OUL 35
Modify Date: 2025-08-26 23:28:46
OUL 35 structure
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Common Name | OUL 35 | ||
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| CAS Number | 6336-34-1 | Molecular Weight | 256.25700 | |
| Density | 1.298g/cm3 | Boiling Point | 488.8ºC at 760 mmHg | |
| Molecular Formula | C14H12N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 257.9ºC | |
Use of OUL 35OUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM[1]. |
| Name | 4-(4-carbamoylphenoxy)benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | OUL35 (NSC39047) is a potent and selective inhibitor of ARTD10 (PARP-10), with an IC50 of 329 nM[1]. |
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| Related Catalog | |
| Target |
ARTD10/PARP10:329 nM (IC50) |
| In Vitro | OUL35 rescues HeLa cells from ARTD10-induced cell death and sensitizes cells to DNA damage. OUL35 (3 μM) binds to endogenous ARTD10 in U2OS cells[1]. OUL35 also inhibits ARTD8 (23.4 μM), ARTD4 (22.6 μM), and ARTD15 (4.17 μM) but with modest potency[1]. OUL35 makes hydrogen bonds to the amide and carbonyl of Gly888 and to the side-chain hydroxyl of Ser927. OUL35 stacks between Tyr919 and Tyr932, like 3AB in the crystal structure[1]. |
| References |
| Density | 1.298g/cm3 |
|---|---|
| Boiling Point | 488.8ºC at 760 mmHg |
| Molecular Formula | C14H12N2O3 |
| Molecular Weight | 256.25700 |
| Flash Point | 257.9ºC |
| Exact Mass | 256.08500 |
| PSA | 95.41000 |
| LogP | 3.07730 |
| Index of Refraction | 1.633 |
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OUL 35 CAS#:6336-34-1 |
| Literature: Eblinger, Frank; Schneider, Hans-Joerg Chemical Communications, 1998 , # 21 p. 2297 - 2298 |
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OUL 35 CAS#:6336-34-1 |
| Literature: Eblinger, Frank; Schneider, Hans-Joerg Chemical Communications, 1998 , # 21 p. 2297 - 2298 |
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OUL 35 CAS#:6336-34-1 |
| Literature: Hopff; Ohlinger Angewandte Chemie, 1949 , vol. 61, p. 183 Chem.Abstr., 1949 , p. 6183 |
CAS#:2215-89-6| 4.4'-Oxy-bis-benzamid |
| 4,4'-oxy-di-benzoic acid diamide |
| 4,4'-oxydibenzamide |
| 4,4'-Oxy-di-benzoesaeure-diamid |