gomisin G

Modify Date: 2024-01-03 10:11:16

gomisin G structure	Common Name	gomisin G
	CAS Number	62956-48-3	Molecular Weight	536.570
	Density	1.3±0.1 g/cm3	Boiling Point	670.9±55.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₃₂O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	217.2±25.0 °C

Use of gomisin G

Gomisin G is an ethanolic extract of the stems of Kadsura interior; exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.

Name	gomisin G
Synonym	More Synonyms

Description	Gomisin G is an ethanolic extract of the stems of Kadsura interior; exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Natural Products >> Phenylpropanoids Research Areas >> Infection
References	[1]. Chen DF, et al. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23. [2]. Ikeya Y, et al. The constituents of Schizandra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem Pharm Bull (Tokyo). 1979 Jun;27(6):1383-94.

Description

Gomisin G is an ethanolic extract of the stems of Kadsura interior; exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.

Related Catalog

Signaling Pathways >> Anti-infection >> HIV

Natural Products >> Phenylpropanoids

Research Areas >> Infection

References

[1]. Chen DF, et al. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23.

[2]. Ikeya Y, et al. The constituents of Schizandra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem Pharm Bull (Tokyo). 1979 Jun;27(6):1383-94.

Density	1.3±0.1 g/cm3
Boiling Point	670.9±55.0 °C at 760 mmHg
Molecular Formula	C₃₀H₃₂O₉
Molecular Weight	536.570
Flash Point	217.2±25.0 °C
Exact Mass	536.204651
PSA	101.91000
LogP	6.38
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.623
Storage condition	2-8℃