Gomisin N

Modify Date: 2024-01-10 15:11:56

Gomisin N structure	Common Name	Gomisin N
	CAS Number	69176-52-9	Molecular Weight	400.465
	Density	1.148±0.06 g/cm3	Boiling Point	545.0±50.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₈O₆	Melting Point	104-108 ºC
	MSDS	N/A	Flash Point	220.4±30.0 °C

Use of Gomisin N

Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. Gomisin N has the potential for use in the treatment of allergy. Gomisin N is an anti-cancer drug candidate capable of inhibiting the proliferation and inducing the apoptosis in cancer[1][2][3].

Name	Gomisin N
Synonym	More Synonyms

Description	Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. Gomisin N has the potential for use in the treatment of allergy. Gomisin N is an anti-cancer drug candidate capable of inhibiting the proliferation and inducing the apoptosis in cancer[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Zhang C, et al. Gomisin N isolated from Schisandra chinensis augments pentobarbital-induced sleep behaviors through the modification of the serotonergic and GABAergic system. Fitoterapia. 2014 Jul;96:123-30. [2]. Chae HS, et al. Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrow-derived mast cells. Immunopharmacol Immunotoxicol. 2011 Dec;33(4):709-13. [3]. Yim SY, et al. Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apoptotic effects in hepatic carcinoma. Mol Med Rep. 2009 Sep-Oct;2(5):725-32.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

References

[1]. Zhang C, et al. Gomisin N isolated from Schisandra chinensis augments pentobarbital-induced sleep behaviors through the modification of the serotonergic and GABAergic system. Fitoterapia. 2014 Jul;96:123-30.

[2]. Chae HS, et al. Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrow-derived mast cells. Immunopharmacol Immunotoxicol. 2011 Dec;33(4):709-13.

[3]. Yim SY, et al. Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apoptotic effects in hepatic carcinoma. Mol Med Rep. 2009 Sep-Oct;2(5):725-32.

Density	1.148±0.06 g/cm3
Boiling Point	545.0±50.0 °C at 760 mmHg
Melting Point	104-108 ºC
Molecular Formula	C₂₃H₂₈O₆
Molecular Weight	400.465
Flash Point	220.4±30.0 °C
Exact Mass	400.188599
PSA	55.38000
LogP	6.46
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.543
Storage condition	2-8°C
Water Solubility	Insuluble (1.0E-3 g/L) (25 ºC)