Tos-PEG9

Modify Date: 2025-09-20 08:50:17

Tos-PEG9 Structure
Tos-PEG9 structure
Common Name Tos-PEG9
CAS Number 62573-11-9 Molecular Weight 568.67500
Density N/A Boiling Point N/A
Molecular Formula C25H44O12S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG9


Tos-PEG9 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name nonaethyleneglycol mono(p-toluenesulfonyl) ether
Synonym More Synonyms

 Tos-PEG9 Biological Activity

Description Tos-PEG9 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H44O12S
Molecular Weight 568.67500
Exact Mass 568.25500
PSA 145.82000
LogP 1.90620
InChIKey IJODQQRFMNRBNF-UHFFFAOYSA-N
SMILES Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCO)cc1

 Synonyms

26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosyl p-toluenesulfonate
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