109635-64-5

109635-64-5 structure

Name: Tos-PEG9-Tos
Chemical Name: Nonaethylene glycol ditosylate
CAS Number: 109635-64-5
Molecular Formula: C₃₂H₅₀O₁₄S₂
Molecular Weight: 722.86100
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-08-24 11:00:31
Modify Date: 2024-01-02 17:43:11
Tos-PEG9-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Nonaethylene glycol ditosylate

Description	Tos-PEG9-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562