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62573-11-9

62573-11-9 structure
62573-11-9 structure
  • Name: Tos-PEG9
  • Chemical Name: nonaethyleneglycol mono(p-toluenesulfonyl) ether
  • CAS Number: 62573-11-9
  • Molecular Formula: C25H44O12S
  • Molecular Weight: 568.67500
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-02-09 02:24:04
  • Modify Date: 2025-09-20 08:50:17
  • Tos-PEG9 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name nonaethyleneglycol mono(p-toluenesulfonyl) ether
Synonyms 26-hydroxy-3,6,9,12,15,18,21,24-octaoxahexacosyl p-toluenesulfonate
Description Tos-PEG9 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H44O12S
Molecular Weight 568.67500
Exact Mass 568.25500
PSA 145.82000
LogP 1.90620
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