2,4-Dihydroxy-5-nitropyrimidine

Modify Date: 2024-01-02 09:28:37

2,4-Dihydroxy-5-nitropyrimidine Structure
2,4-Dihydroxy-5-nitropyrimidine structure
Common Name 2,4-Dihydroxy-5-nitropyrimidine
CAS Number 611-08-5 Molecular Weight 157.084
Density 1.9±0.1 g/cm3 Boiling Point 453.3±48.0 °C at 760 mmHg
Molecular Formula C4H3N3O4 Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 227.9±29.6 °C

 Use of 2,4-Dihydroxy-5-nitropyrimidine


 

 Names

Name 5-Nitrouracil
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 453.3±48.0 °C at 760 mmHg
Melting Point >300 °C(lit.)
Molecular Formula C4H3N3O4
Molecular Weight 157.084
Flash Point 227.9±29.6 °C
Exact Mass 157.012360
PSA 111.54000
LogP -1.72
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.701
Storage condition -20°C Freezer

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes C: Corrosive;F: Flammable;
Risk Phrases R11
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS UV9104545
HS Code 2933599090

 Synthetic Route

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles8

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Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.

Antimicrob. Agents Chemother. 58(12) , 7475-83, (2014)

We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated wit...

Inhibition of UDP-glucuronyltransferase activity in rat liver microsomes by pyrimidine derivatives.

Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 112(3) , 321-5, (1995)

Thirty-one differently substituted pyrimidine bases were tested for their inhibitory effect on the glucuronidation of 4-nitrophenol and phenolphthalein by rat liver microsomes. 5-Nitrouracil (compound...

Thymidine phosphorylase inhibitors with a homophthalimide skeleton.

Biol. Pharm. Bull. 24(7) , 860-2, (2001)

Several N-phenylhomophthalimide derivatives were prepared and their inhibitory activity on thymidine phosphorylase/ platelet-derived endothelial cell growth factor (TP/PD-ECGF) was assessed. Among the...

 Synonyms

2,4(1H,3H)-Pyrimidinedione, 5-nitro-
5-nitropyrimidine-2,4(1H,3H)-dione
5-NITRO-2,4-PYRIMIDINEDIOL
5-Nitro-2,4(1H,3H)-pyrimidinedione
5-nitro-1H-pyrimidine-2,4-dione
5-nitropyrimidine-2,4-diol
MFCD00006021
2,4-Dihydroxy-5-Nitropyrimidine
5-Nitro-1H-pyrimidin-2,4-dion
5-Nitropyrimidin-2,4(1H,3H)-dion
NITROURACIL
Uracil,5-nitro
4(1H)-pyrimidinone, 2-hydroxy-5-nitro-
2-Hydroxy-5-nitropyrimidin-4(1H)-one
5-nitro-uracil
EINECS 210-250-4
5-NITROURACIL extrapure