Bromperidol hydrochloride

Modify Date: 2025-08-25 21:55:26

Bromperidol hydrochloride structure	Common Name	Bromperidol hydrochloride
	CAS Number	59453-24-6	Molecular Weight	456.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₄BrClFNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bromperidol hydrochloride

Bromperidol hydrochloride (R-11333 hydrochloride) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill mycobacteria in a synergistic manner with Spectinomycin[1][2].

Name	Bromperidol hydrochloride

Description	Bromperidol hydrochloride (R-11333 hydrochloride) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill mycobacteria in a synergistic manner with Spectinomycin[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial
Target	D2 Receptor
In Vivo	Bromperidol hydrochloride antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats[1]. Bromperidol hydrochloride antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs[1].
References	[1]. Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35(6):670-84. [2]. Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9.

Molecular Formula	C₂₁H₂₄BrClFNO₂
Molecular Weight	456.78
InChIKey	XAYXCUZHMISKSM-UHFFFAOYSA-N
SMILES	Cl.O=C(CCCN1CCC(O)(c2ccc(Br)cc2)CC1)c1ccc(F)cc1

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Product Name: Bromperidol hydrochloride
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