Bromperidol hydrochloride

Modify Date: 2024-01-10 18:27:45

Bromperidol hydrochloride Structure
Bromperidol hydrochloride structure
Common Name Bromperidol hydrochloride
CAS Number 59453-24-6 Molecular Weight 456.78
Density N/A Boiling Point N/A
Molecular Formula C21H24BrClFNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromperidol hydrochloride


Bromperidol hydrochloride (R-11333 hydrochloride) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill mycobacteria in a synergistic manner with Spectinomycin[1][2].

 Names

Name Bromperidol hydrochloride

 Bromperidol hydrochloride Biological Activity

Description Bromperidol hydrochloride (R-11333 hydrochloride) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride can kill mycobacteria in a synergistic manner with Spectinomycin[1][2].
Related Catalog
Target

D2 Receptor

In Vivo Bromperidol hydrochloride antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats[1]. Bromperidol hydrochloride antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs[1].
References

[1]. Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35(6):670-84.

[2]. Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9.

 Chemical & Physical Properties

Molecular Formula C21H24BrClFNO2
Molecular Weight 456.78
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