Met-Enkephalin acetate salt

Modify Date: 2024-01-02 17:21:26

Met-Enkephalin acetate salt Structure
Met-Enkephalin acetate salt structure
Common Name Met-Enkephalin acetate salt
CAS Number 58569-55-4 Molecular Weight 573.66100
Density 1.324 g/cm3 Boiling Point 1052.9ºC at 760 mmHg
Molecular Formula C27H35N5O7S Melting Point N/A
MSDS N/A Flash Point 590.6ºC

 Use of Met-Enkephalin acetate salt


Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

 Names

Name 2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid
Synonym More Synonyms

 Met-Enkephalin acetate salt Biological Activity

Description Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
Related Catalog
Target

Opioid Receptor[1].

In Vitro Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1].
References

[1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.

 Chemical & Physical Properties

Density 1.324 g/cm3
Boiling Point 1052.9ºC at 760 mmHg
Molecular Formula C27H35N5O7S
Molecular Weight 573.66100
Flash Point 590.6ºC
Exact Mass 573.22600
PSA 225.25000
LogP 1.80830
Index of Refraction 1.608
Storage condition −20°C

 Safety Information

Safety Phrases S22-S24/25
WGK Germany 3

 Synthetic Route

 Synonyms

MET-enkephalin
ENKEPHALIN,METHIONINE
1-5-Adrenorphin (human)
H-Tyr(1)-Gly(2)-Gly(3)-Phe(4)-Met(5)-OH
Methionine enkephalin
[Met5]-enkephalin
TYR-GLY-GLY-PHE-MET
Opioid growth factor
H-Tyr-Gly-Gly-Phe-Met-OH
EINECS 261-335-8
Tyr-Gly-Gly-Phe-Met-OH
Lupex
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