Acridone

Modify Date: 2025-08-25 12:29:34

Acridone Structure
Acridone structure
Common Name Acridone
CAS Number 578-95-0 Molecular Weight 195.217
Density 1.2±0.1 g/cm3 Boiling Point 355.0±12.0 °C at 760 mmHg
Molecular Formula C13H9NO Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 155.0±19.7 °C

 Use of Acridone


Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities[1].

 Names

Name Acridone
Synonym More Synonyms

 Acridone Biological Activity

Description Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities[1].
Related Catalog
References

[1]. Licheng Xu, et al. Acridone suppresses the proliferation of human breast cancer cells in vitro via ATP-binding cassette subfamily G member 2. Oncol Lett. 2018 Feb; 15(2): 2651-2654.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 355.0±12.0 °C at 760 mmHg
Melting Point >300 °C(lit.)
Molecular Formula C13H9NO
Molecular Weight 195.217
Flash Point 155.0±19.7 °C
Exact Mass 195.068420
PSA 32.86000
LogP 2.57
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.642

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR6976000
CHEMICAL NAME :
9-Acridanone
CAS REGISTRY NUMBER :
578-95-0
BEILSTEIN REFERENCE NO. :
0007104
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H9-N-O
MOLECULAR WEIGHT :
195.23
WISWESSER LINE NOTATION :
T C666 BM IVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
10 pph
REFERENCE :
BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 11,2537,1972

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AR6976000
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles31

More Articles
Copper-catalyzed intramolecular oxidative C-H functionalization and C-N formation of 2-aminobenzophenones: unusual pseudo-1,2-shift of the substituent on the aryl ring.

Chemistry 19(2) , 460-4, (2013)

Online Investigation of Aqueous-Phase Electrochemical Reactions by Desorption Electrospray Ionization Mass Spectrometry.

J. Am. Soc. Mass Spectrom. 26 , 1676-85, (2015)

Electrochemistry (EC) combined with mass spectrometry (MS) is a powerful tool for elucidation of electrochemical reaction mechanisms. However, direct online analysis of electrochemical reaction in aqu...

Extravascular transport of drugs in tumor tissue: effect of lipophilicity on diffusion of tirapazamine analogues in multicellular layer cultures.

J. Med. Chem. 48 , 1079-87, (2005)

The extravascular diffusion of antitumor agents is a key determinant of their therapeutic activity, but the relationships between physicochemical properties of drugs and their extravascular transport ...

 Synonyms

9-acridinol
ACRIDON
Acrodone
EINECS 209-434-7
Acridanone
indenone
9(10H)-Acridone
Acridone
Acridin-9-ol
9,10-dihydroacridin-9-one
9(10H)-Acridinone
9-oxo-9,10-dihydroacridine
CK 103
9-Acridone
MFCD00005019
acridin-9(10H)-one
Acridin-9(10H)-on
Oxcarbazepine Impurity 13
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