Nialamide
Modify Date: 2024-01-11 02:00:27
Nialamide structure
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Common Name | Nialamide | ||
|---|---|---|---|---|
| CAS Number | 51-12-7 | Molecular Weight | 298.34000 | |
| Density | 1.203g/cm3 | Boiling Point | 538.1ºC at 760mmHg | |
| Molecular Formula | C16H18N4O2 | Melting Point | 152-154ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 279.2ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
Use of NialamideNialamide is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant. |
| Name | N-benzyl-3-[2-(pyridine-4-carbonyl)hydrazinyl]propanamide |
|---|---|
| Synonym | More Synonyms |
| Description | Nialamide is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant. |
|---|---|
| Related Catalog |
| Density | 1.203g/cm3 |
|---|---|
| Boiling Point | 538.1ºC at 760mmHg |
| Melting Point | 152-154ºC(lit.) |
| Molecular Formula | C16H18N4O2 |
| Molecular Weight | 298.34000 |
| Flash Point | 279.2ºC |
| Exact Mass | 298.14300 |
| PSA | 83.12000 |
| LogP | 2.19520 |
| Index of Refraction | 1.589 |
| Water Solubility | ethanol: clear to hazy |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332-H315-H319-H335-H351 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 20/21/22-36/37/38-40 |
| Safety Phrases | S22;S26;S36 |
| RIDADR | UN 3249 |
| WGK Germany | 3 |
| RTECS | NS1225000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for determination of isoniazid in human plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(3) , 285-90, (2009) An LC-MS/MS method for the determination of isoniazid in human plasma was developed and validated. Human plasma aliquots of 100 microL were used for analysis. The assay used nialamide as the internal ... |
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UWA-121, a mixed dopamine and serotonin re-uptake inhibitor, enhances L-DOPA anti-parkinsonian action without worsening dyskinesia or psychosis-like behaviours in the MPTP-lesioned common marmoset.
Neuropharmacology 82 , 76-87, (2014) L-3,4-Dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease (PD), but its long-term administration is complicated by wearing-off and dyskinesia. UWA-101, a dual, equi... |
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Spinal cord injury enables aromatic L-amino acid decarboxylase cells to synthesize monoamines.
J. Neurosci. 34(36) , 11984-2000, (2014) Serotonin (5-HT), an important modulator of both sensory and motor functions in the mammalian spinal cord, originates mainly in the raphe nuclei of the brainstem. However, following complete transecti... |
| 4-pyridinecarboxylic acid |
| Nialamid |
| N-[2-(benzylcarbamoyl)ethyl]-N'-isonicotinyl hydrazide |
| N-benzyl-3-(N'-(pyridine-4-carbonyl)hydrazino)propanamide |
| EINECS 200-079-3 |
| Niamidal |
| Niamid |
| Psicodisten |
| MFCD00010106 |
| 2-{3-oxo-3-[(phenylmethyl)amino]propyl}hydrazide |
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| Niazin |
| Nuredal |
| Nyazin |
| N-benzyl-3-(N'-isonicotinoyl-hydrazino)-propionamide |
| Niaquitil |
| Nialamide |