Acetovanillone

Modify Date: 2025-08-21 18:09:24

Acetovanillone structure	Common Name	Acetovanillone
	CAS Number	498-02-2	Molecular Weight	166.174
	Density	1.2±0.1 g/cm3	Boiling Point	297.5±0.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₀O₃	Melting Point	112-115 °C(lit.)
	MSDS	Chinese USA	Flash Point	125.5±15.8 °C
	Symbol	GHS07	Signal Word	Warning

Use of Acetovanillone

Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM.

Name	apocynin
Synonym	More Synonyms

Description	Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Natural Products >> Phenols Research Areas >> Cancer
References	[1]. Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102. [2]. Stefanska J, et al. Mediators Inflamm, 2008, 106507. [3]. Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 1;81(5):636-48.

Description

Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM.

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Natural Products >> Phenols

Research Areas >> Cancer

References

[1]. Stolk J,et al. Am J Respir Cell Mol Biol, 1994, 11(1), 95-102.

[2]. Stefanska J, et al. Mediators Inflamm, 2008, 106507.

[3]. Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 1;81(5):636-48.

Density	1.2±0.1 g/cm3
Boiling Point	297.5±0.0 °C at 760 mmHg
Melting Point	112-115 °C(lit.)
Molecular Formula	C₉H₁₀O₃
Molecular Weight	166.174
Flash Point	125.5±15.8 °C
Exact Mass	166.062988
PSA	46.53000
LogP	1.39
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.538
Storage condition	Refrigerator
Water Solubility	soluble in hot water

Acetovanillone MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM8800000

CHEMICAL NAME :: Acetophenone, 4'-hydroxy-3'-methoxy-

CAS REGISTRY NUMBER :: 498-02-2

BEILSTEIN REFERENCE NO. :: 0637373

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H10-O3

MOLECULAR WEIGHT :: 166.19

WISWESSER LINE NOTATION :: 1VR DQ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 400 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 119,273,1983

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	AM8800000
HS Code	2942000000

Precursor 7
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DownStream 9
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CAS#:18256-48-9 Ethanone, 2-hyd...

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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4'-hydroxy-3'-methoxyacetophenone

MFCD00008747

Acetovanillone

Apocynin

Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-

1-(4-Hydroxy-3-methoxyphenyl)ethanone

EINECS 207-854-5

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China
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Acetovanillone

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