6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one

Modify Date: 2025-08-27 19:24:32

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure
6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one structure
 Common Name 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one
CAS Number 486-28-2 Molecular Weight 222.194
Density 1.4±0.1 g/cm3 Boiling Point 449.7±45.0 °C at 760 mmHg
Molecular Formula C11H10O5 Melting Point 170-172ºC
MSDS N/A Flash Point 182.1±22.2 °C

 Use of 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one


Fraxinol is isolated from Lobelia chinensis[1].

 Names

Name 6-hydroxy-5,7-dimethoxychromen-2-one
Synonym More Synonyms

 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Biological Activity

Description Fraxinol is isolated from Lobelia chinensis[1].
Related Catalog
References

[1]. Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 449.7±45.0 °C at 760 mmHg
Melting Point 170-172ºC
Molecular Formula C11H10O5
Molecular Weight 222.194
Flash Point 182.1±22.2 °C
Exact Mass 222.052826
PSA 68.90000
LogP 0.90
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.588

 Safety Information

Hazard Codes Xi

 Synthetic Route

3,6-dihydroxy-2,4-dimethoxybenzaldehyde structure

3,6-dihydroxy-2...

CAS#:105827-22-3

Methyl triphenylphosphoranylideneacetate structure

Methyl tripheny...

CAS#:21204-67-1

~59%

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure

6-Hydroxy-5,7-d...

CAS#:486-28-2

Literature: Riveiro, Maria E.; Maes, Dominick; Vazquez, Ramiro; Vermeulen, Monica; Mangelinckx, Sven; Jacobs, Jan; Debenedetti, Silvia; Shayo, Carina; De Kimpe, Norbert; Davio, Carlos Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6547 - 6559
6-Formyllimetin structure

6-Formyllimetin

CAS#:88140-31-2

~%

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure

6-Hydroxy-5,7-d...

CAS#:486-28-2

Literature: Ishii; Kobayashi; Ishikawa Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3330 - 3333
2-(5,7-dimethoxy-2-oxo-2H-chromen-6-yl)vinyl acetate structure

2-(5,7-dimethox...

CAS#:88140-32-3

~%

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure

6-Hydroxy-5,7-d...

CAS#:486-28-2

Literature: Ishii; Kobayashi; Ishikawa Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3330 - 3333
acetyl fraxinol structure

acetyl fraxinol

CAS#:28752-90-1

~%

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure

6-Hydroxy-5,7-d...

CAS#:486-28-2

Literature: xxx Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2000 , vol. 39, # 11 p. 879 - 882
Citropten structure

Citropten

CAS#:487-06-9

~%

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure

6-Hydroxy-5,7-d...

CAS#:486-28-2

Literature: Bhavsar; Desai Indian Journal of Pharmacy, 1951 , vol. 13, p. 200,203 Full Text Show Details Dalvi et al. Journal of the Indian Chemical Society, 1951 , vol. 28, p. 366,369
mandshurin structure

mandshurin

CAS#:32451-87-9

~%

D-glucopyranose structure

D-glucopyranose

CAS#:2280-44-6

6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one Structure

6-Hydroxy-5,7-d...

CAS#:486-28-2

Literature: Tsukamoto; Hisada; Nishibe Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 4069 - 4073

 Synonyms

2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-
6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one
6-hydroxy-5,7-dimethoxy-chromen-2-one
6-hydroxy-5,7-dimethoxycoumarin
5,7-dimethoxy-6-hydroxycoumarin
Fraxinol
6-Hydroxy-5,7-dimethoxy-cumarin
2H-1-Benzopyran-2-one,6-hydroxy-5,7-dimethoxy
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Chemsrc provides 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one(CAS#:486-28-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one are included as well.>> amp version: 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one

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