486-28-2

486-28-2 structure

Name: 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one
Chemical Name: 6-hydroxy-5,7-dimethoxychromen-2-one
CAS Number: 486-28-2
Molecular Formula: C₁₁H₁₀O₅
Molecular Weight: 222.194
Catalog: Natural product Coumarin
Create Date: 2018-02-27 08:00:00
Modify Date: 2025-08-27 19:24:32
Fraxinol is isolated from Lobelia chinensis[1].

Name	6-hydroxy-5,7-dimethoxychromen-2-one
Synonyms	2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy- 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one 6-hydroxy-5,7-dimethoxy-chromen-2-one 6-hydroxy-5,7-dimethoxycoumarin 5,7-dimethoxy-6-hydroxycoumarin Fraxinol 6-Hydroxy-5,7-dimethoxy-cumarin 2H-1-Benzopyran-2-one,6-hydroxy-5,7-dimethoxy

Description	Fraxinol is isolated from Lobelia chinensis[1].
Related Catalog	Research Areas >> Others
References	[1]. Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367.

Density	1.4±0.1 g/cm3
Boiling Point	449.7±45.0 °C at 760 mmHg
Melting Point	170-172ºC
Molecular Formula	C₁₁H₁₀O₅
Molecular Weight	222.194
Flash Point	182.1±22.2 °C
Exact Mass	222.052826
PSA	68.90000
LogP	0.90
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.588

Hazard Codes	Xi

105827-22-3

21204-67-1

~59%

486-28-2

Literature: Riveiro, Maria E.; Maes, Dominick; Vazquez, Ramiro; Vermeulen, Monica; Mangelinckx, Sven; Jacobs, Jan; Debenedetti, Silvia; Shayo, Carina; De Kimpe, Norbert; Davio, Carlos Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6547 - 6559

88140-31-2

486-28-2

Literature: Ishii; Kobayashi; Ishikawa Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3330 - 3333

88140-32-3

486-28-2

Literature: Ishii; Kobayashi; Ishikawa Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3330 - 3333

28752-90-1

486-28-2

Literature: xxx Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2000 , vol. 39, # 11 p. 879 - 882

487-06-9

486-28-2

Literature: Bhavsar; Desai Indian Journal of Pharmacy, 1951 , vol. 13, p. 200,203 Full Text Show Details Dalvi et al. Journal of the Indian Chemical Society, 1951 , vol. 28, p. 366,369

32451-87-9

2280-44-6

486-28-2

Literature: Tsukamoto; Hisada; Nishibe Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 4069 - 4073

Precursor 6
105827-22-3 88140-31-2 88140-32-3 28752-90-1
487-06-9 32451-87-9
DownStream 1
55085-47-7

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