6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one

Names

[ CAS No. ]:
486-28-2

[ Name ]:
6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one

[Synonym ]:
2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-
6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one
6-hydroxy-5,7-dimethoxy-chromen-2-one
6-hydroxy-5,7-dimethoxycoumarin
5,7-dimethoxy-6-hydroxycoumarin
Fraxinol
6-Hydroxy-5,7-dimethoxy-cumarin
2H-1-Benzopyran-2-one,6-hydroxy-5,7-dimethoxy

Biological Activity

[Description]:

Fraxinol is isolated from Lobelia chinensis[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
449.7±45.0 °C at 760 mmHg

[ Melting Point ]:
170-172ºC

[ Molecular Formula ]:
C₁₁H₁₀O₅

[ Molecular Weight ]:
222.194

[ Flash Point ]:
182.1±22.2 °C

[ Exact Mass ]:
222.052826

[ PSA ]:
68.90000

[ LogP ]:
0.90

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.588

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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