Cotoin

Modify Date: 2025-08-25 15:50:27

Cotoin structure	Common Name	Cotoin
	CAS Number	479-21-0	Molecular Weight	244.243
	Density	1.3±0.1 g/cm3	Boiling Point	402.2±45.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₂O₄	Melting Point	131-132°
	MSDS	N/A	Flash Point	153.3±22.2 °C

Use of Cotoin

Cotoin is a natural product isolated from the stem bark of Garcinia virgate[1].

Name	(2,6-dihydroxy-4-methoxyphenyl)-phenylmethanone
Synonym	More Synonyms

Description	Cotoin is a natural product isolated from the stem bark of Garcinia virgate[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Merza J, et al. Prenylated xanthones and tocotrienols from Garcinia virgata. Phytochemistry. 2004 Nov;65(21):2915-20.

Density	1.3±0.1 g/cm3
Boiling Point	402.2±45.0 °C at 760 mmHg
Melting Point	131-132°
Molecular Formula	C₁₄H₁₂O₄
Molecular Weight	244.243
Flash Point	153.3±22.2 °C
Exact Mass	244.073563
PSA	66.76000
LogP	4.07
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.624

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ1050000

CHEMICAL NAME :: Benzophenone, 2,6-dihydroxy-4-methoxy-

CAS REGISTRY NUMBER :: 479-21-0

BEILSTEIN REFERENCE NO. :: 1981817

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H12-O4

MOLECULAR WEIGHT :: 244.26

WISWESSER LINE NOTATION :: 1OR CQ EQ DVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 242 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Cardiac - change in force of contraction Lungs, Thorax, or Respiration - other changes

REFERENCE :: BIZEA2 Biochemische Zeitschrift. (Berlin, Ger.) V.1-346, 1906-67. For publisher information, see EJBCAI. Volume(issue)/page/year: 74,340,1916

flamenol

CAS#:2174-64-3

Benzoyl chloride

CAS#:98-88-4

~67%

Cotoin

CAS#:479-21-0

Literature: Mitasev, Branko; Porco Jr., John A. Organic Letters, 2009 , vol. 11, # 11 p. 2285 - 2288

Benzoyl chloride

CAS#:98-88-4

Cotoin

CAS#:479-21-0

Literature: Thevenin, Marion; Mouray, Elisabeth; Grellier, Philippe; Dubois, Joelle European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2986 - 2992

1,3,5-Trimethox...

CAS#:621-23-8

Cotoin

CAS#:479-21-0

Literature: Thevenin, Marion; Mouray, Elisabeth; Grellier, Philippe; Dubois, Joelle European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2986 - 2992

diazomethane

CAS#:186581-53-3

Cotoin

CAS#:479-21-0

Literature: Spaeth; Fuchs Monatshefte fuer Chemie, 1921 , vol. 42, p. 272

4-methoxy-3-met...

CAS#:125557-63-3

Cotoin

CAS#:479-21-0

Literature: Harris,T.M.; Wachter,M.P. Tetrahedron, 1970 , vol. 26, p. 5255 - 5263

phenyl-(2,4,6-t...

CAS#:3770-80-7

~4%

Cotoin

CAS#:479-21-0

2,4,6-Trihydrox...

CAS#:3555-86-0

Literature: Thevenin, Marion; Mouray, Elisabeth; Grellier, Philippe; Dubois, Joelle European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2986 - 2992

flamenol

CAS#:2174-64-3

Benzoyl chloride

CAS#:98-88-4

Cotoin

CAS#:479-21-0

isocotoin

CAS#:81525-12-4

Literature: Iinuma, Munekazu; Tosa, Hideki; Ito, Tetsuro; Tanaka, Toshiyuki; Riswan, Soedarsono Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 9 p. 1744 - 1747

diazomethane

CAS#:186581-53-3

Diethyl ether

CAS#:60-29-7

2,4,6-Trihydrox...

CAS#:3555-86-0

Cotoin

CAS#:479-21-0

Detail

Literature: Spaeth; Fuchs Monatshefte fuer Chemie, 1921 , vol. 42, p. 272

Precursor 8
CAS#:2174-64-3 flamenol CAS#:98-88-4 Benzoyl chloride CAS#:3770-80-7 phenyl-(2,4,6-t... CAS#:621-23-8 1,3,5-Trimethox...
CAS#:186581-53-3 diazomethane CAS#:125557-63-3 4-methoxy-3-met... CAS#:60-29-7 Diethyl ether CAS#:3555-86-0 2,4,6-Trihydrox...
DownStream 3
CAS#:108-73-6 Phloroglucinol CAS#:65-85-0 benzoic acid CAS#:2174-64-3 flamenol