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Cotoin

Names

[ CAS No. ]:
479-21-0

[ Name ]:
Cotoin

[Synonym ]:
BENZOPHENONE,2,6-DIHYDROXY-4-METHOXY
Methanone, (2,6-dihydroxy-4-methoxyphenyl)phenyl-
Monomethyl ether of 2,4,6-trihydroxybenzophenone
2,6-Dihydroxy-4-methoxy-benzophenon
Cotoin
(2,6-Dihydroxy-4-methoxyphenyl)(phenyl)methanone
2,6-Dihydroxy-4-methoxybenzophenone

Biological Activity

[Description]:

Cotoin is a natural product isolated from the stem bark of Garcinia virgate[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Merza J, et al. Prenylated xanthones and tocotrienols from Garcinia virgata. Phytochemistry. 2004 Nov;65(21):2915-20.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
402.2±45.0 °C at 760 mmHg

[ Melting Point ]:
131-132°

[ Molecular Formula ]:
C14H12O4

[ Molecular Weight ]:
244.243

[ Flash Point ]:
153.3±22.2 °C

[ Exact Mass ]:
244.073563

[ PSA ]:
66.76000

[ LogP ]:
4.07

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.624

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ1050000
CHEMICAL NAME :
Benzophenone, 2,6-dihydroxy-4-methoxy-
CAS REGISTRY NUMBER :
479-21-0
BEILSTEIN REFERENCE NO. :
1981817
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H12-O4
MOLECULAR WEIGHT :
244.26
WISWESSER LINE NOTATION :
1OR CQ EQ DVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
242 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Cardiac - change in force of contraction Lungs, Thorax, or Respiration - other changes
REFERENCE :
BIZEA2 Biochemische Zeitschrift. (Berlin, Ger.) V.1-346, 1906-67. For publisher information, see EJBCAI. Volume(issue)/page/year: 74,340,1916

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream