Methyl 2-chloroacetoacetate

Modify Date: 2024-01-05 10:01:24

Methyl 2-chloroacetoacetate structure	Common Name	Methyl 2-chloroacetoacetate
	CAS Number	4755-81-1	Molecular Weight	150.56000
	Density	1.236 g/mL at 25 °C(lit.)	Boiling Point	137 °C(lit.)
	Molecular Formula	C₅H₇ClO₃	Melting Point	−33-−32.7 °C(lit.)
	MSDS	Chinese USA	Flash Point	161 °F
	Symbol	GHS07	Signal Word	Warning

Name	Methyl 2-chloroacetoacetate
Synonym	More Synonyms

Density	1.236 g/mL at 25 °C(lit.)
Boiling Point	137 °C(lit.)
Melting Point	−33-−32.7 °C(lit.)
Molecular Formula	C₅H₇ClO₃
Molecular Weight	150.56000
Flash Point	161 °F
Exact Mass	150.00800
PSA	43.37000
LogP	0.35580
Index of Refraction	n20/D 1.446(lit.)
Storage condition	2~8°C
Water Solubility	50 g/L (20 ºC)

Methyl 2-chloroacetoacetate MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn: Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S27-S28-S36/37/39-S37/39
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
Packaging Group	III
Hazard Class	8
HS Code	29183000

Methyl acetoacetate

CAS#:105-45-3

~98%

Methyl 2-chloro...

CAS#:4755-81-1

Literature: Li, Ze; Khaliq, Mansoora; Zhou, Zhigang; Post, Carol Beth; Kuhn, Richard J.; Cushman, Mark Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4660 - 4671

Ethyl acetoacetate

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Methyl 2-chloro...

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Ethyl 2-Chloroa...

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Literature: Chen, Zizhan; Zhou, Bin; Cai, Huihua; Zhu, Wei; Zou, Xinzhuo Green Chemistry, 2009 , vol. 11, # 2 p. 275 - 278

methyl 2,2-dich...

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Methyl 2-chloro...

CAS#:4755-81-1

Literature: Villeras,J. Journal of Organometallic Chemistry, 1972 , vol. 34, p. 209 - 219

Precursor 3
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DownStream 9
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HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Chemoselective arylamidine cyclizations: mild formation of 2-arylimidazole-4-carboxylic acids.

Org. Lett. 7(17) , 3801-3, (2005)

A versatile, one-pot synthesis of 2-arylimidazole-4-carboxylic acids from arylamidines and methyl-2-chloroacetoacetate is described. The transformation is chemoselective, and reaction conditions are m...

'One-flask'synthesis to 3, 5-disubstituted 1, 2, 4-triazoles from aldehydes with hydrazonoyl hydrochlorides via 1, 3-dipolar cycloaddition. Tseng W-C, et al.

Tetrahedron 67(29) , 5339-45, (2011)

2-Chloroacetoacetic Acid Methyl Ester

MFCD00008757

Methyl 2-Chloroacetoacetate

methyl 2-chloro-3-oxobutanoate

EINECS 225-286-6