Methyl acetoacetate

Modify Date: 2025-08-20 19:30:06

Methyl acetoacetate structure	Common Name	Methyl acetoacetate
	CAS Number	105-45-3	Molecular Weight	116.115
	Density	1.0±0.1 g/cm3	Boiling Point	169.4±8.0 °C at 760 mmHg
	Molecular Formula	C₅H₈O₃	Melting Point	-28 °C
	MSDS	Chinese USA	Flash Point	61.6±18.5 °C
	Symbol	GHS07	Signal Word	Warning

Name	Methyl acetoacetate
Synonym	More Synonyms

Density	1.0±0.1 g/cm3
Boiling Point	169.4±8.0 °C at 760 mmHg
Melting Point	-28 °C
Molecular Formula	C₅H₈O₃
Molecular Weight	116.115
Flash Point	61.6±18.5 °C
Exact Mass	116.047340
PSA	43.37000
LogP	0.19
Vapour Pressure	1.5±0.3 mmHg at 25°C
Index of Refraction	1.399
Storage condition	2-8°C
Water Solubility	460 g/L (20 ºC)

Methyl acetoacetate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AK5775000

CHEMICAL NAME :: Acetoacetic acid, methyl ester

CAS REGISTRY NUMBER :: 105-45-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C5-H8-O3

MOLECULAR WEIGHT :: 116.13

WISWESSER LINE NOTATION :: 1V1VO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,815,1978

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3228 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84355 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 270 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84355 No. of Facilities: 30 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1872 (estimated) No. of Female Employees: 336 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36
Safety Phrases	S26
WGK Germany	1
RTECS	AK5775000
HS Code	2918300090

Precursor 10
CAS#:674-82-8 Diketene CAS#:67-56-1 Methanol CAS#:1694-31-1 tert-Butyl acet... CAS#:623-43-8 Methyl (2E)-2-b...
CAS#:1487-49-6 methyl 3-hydrox... CAS#:79-20-9 Methyl acetate CAS#:77-92-9 Citric Acid CAS#:2033-24-1 Meldrumic acid
CAS#:75-36-5 Acetyl chloride CAS#:201230-82-2 carbon monoxide
DownStream 10
CAS#:105702-03-2 1,4-diacetyl-3-... CAS#:100-02-7 4-Nitrophenol CAS#:689-67-8 6,10-Dimethyl-5... CAS#:141-10-6 PSEUDOIONONE
CAS#:134143-47-8 10-methyl-6-met... CAS#:105737-79-9 10-methyl-6-met... CAS#:104990-30-9 methyl 2-[(2,4-... CAS#:53779-37-6 (5E,8Z)-6,10-di...
CAS#:105553-49-9 10-methyl-6-met... CAS#:100063-41-0 5-Methyl-2-phen...

HS Code	2918300090
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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EINECS 203-299-8

Methyl 3-oxobutanoate

Butanoic acid, 3-oxo-, methyl ester

Methyl acetoacetate

3-Oxobutyric acid methyl ester

Acetoacetic Acid Methyl Ester

methyl acetoacetate(MAA)

MFCD00008784

Methyl 3-Oxobutyrate

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Methyl acetoacetate
Price: Check
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Methyl acetoacetate
Price: ￥148.0/500g
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methyl acetoacetate suppliers in China
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Methyl acetoacetate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Methyl acetoacetate
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Methyl acetoacetate

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