Meldrumic acid

Modify Date: 2024-01-02 11:58:56

Meldrumic acid structure	Common Name	Meldrumic acid
	CAS Number	2033-24-1	Molecular Weight	144.13
	Density	1.2±0.1 g/cm3	Boiling Point	356.7±35.0 °C at 760 mmHg
	Molecular Formula	C₆H₈O₄	Melting Point	92-96 °C(lit.)
	MSDS	Chinese USA	Flash Point	195.1±24.4 °C

Use of Meldrumic acid

2,2-Dimethyl-1,3-dioxane-4,6-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	Meldrum's acid
Synonym	More Synonyms

Description	2,2-Dimethyl-1,3-dioxane-4,6-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others

Density	1.2±0.1 g/cm3
Boiling Point	356.7±35.0 °C at 760 mmHg
Melting Point	92-96 °C(lit.)
Molecular Formula	C₆H₈O₄
Molecular Weight	144.13
Flash Point	195.1±24.4 °C
Exact Mass	144.042252
PSA	52.60000
LogP	-1.40
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.434
Storage condition	0-6°C
Water Solubility	2.5 g/100 mL (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JH0800000

CHEMICAL NAME :: m-Dioxane-4,6-dione, 2,2-dimethyl-

CAS REGISTRY NUMBER :: 2033-24-1

BEILSTEIN REFERENCE NO. :: 0117310

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H8-O4

MOLECULAR WEIGHT :: 144.14

WISWESSER LINE NOTATION :: T6OV DVOTJ F1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04102

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi,T
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin . R45:May cause cancer.
Safety Phrases	S37/39-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	JH0800000
HS Code	2934999090

Precursor 10
CAS#:141-82-2 Malonic acid CAS#:67-64-1 Acetone CAS#:108-24-7 Ethanoic anhydride CAS#:68695-08-9 6,6-dimethyl-5,...
CAS#:108-22-5 Isopropenyl acetate CAS#:594-71-8 Propane,2-chlor... CAS#:996-82-7 sodium 1,3-diet... CAS#:34107-52-3 2-phenyliodonio...
CAS#:1214-54-6 2,2-DIMETHYL-5-... CAS#:7270-63-5 5-Diazo-2,2-dim...
DownStream 10
CAS#:111861-18-8 2,2-dimethyl-5-... CAS#:109610-93-7 1,3-Dioxane-4,6... CAS#:111286-54-5 2,2-dimethyl-5-... CAS#:108446-77-1 1,3-DIPHENYLPYR...
CAS#:108446-79-3 3-(4-CHLOROPHEN... CAS#:55804-65-4 Coumarin 343 CAS#:606-83-7 3,3-Diphenylpro... CAS#:3855-87-6 6,8-dibromocoum...
CAS#:55107-14-7 Methyl 4,4-dime... CAS#:30818-11-2 1-(PIPERIDIN-4-...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents.

Bioorg. Med. Chem. 18 , 5626-33, (2010)

A series of arylidene analogues of Meldrum's acid were synthesized and evaluated for in vitro antimalarial and antioxidant activities for the first time. The influence of various physico-chemical para...

One hundred years of Meldrum's acid: advances in the synthesis of pyridine and pyrimidine derivatives.

Mol. Divers. 13(4) , 399-419, (2009)

A general review (138 references) focused on the recent advances in the application of Meldrum's acid reactivity for synthesis of diverse pyridine and pyrimidine derivatives, mostly small and drug-lik...

A new domino autocatalytic reaction leading to polyfunctionalized spiro[5.5]undecanes and dispiro[4.2.5.2]pentadecanes.

Org. Biomol. Chem. 7(10) , 2195-201, (2009)

A new domino autocatalytic reaction of imines with Meldrum's acid was described. In this reaction, a series of polycyclic spiro[5.5]undecane-1,5,9-trione and dispiro[4.2.5.2]pentadecane-9,13-dione der...

sub-Isopropyl malonate

MELDRUMS ACID

Malonic acid cyclic isopropylidene ester

Isopropyl Malonate

Meldrumacid

isopropylidene malonate

Meldrumic acid

Meldrum’s acid

1,3-Dioxane-4,6-dione, 2,2-dimethyl-

2,2-Dimethyl-1,3-dioxane-4,6-dione

cycl-Isopropylidene Malonate

2,2-Dimethyl-1,3-dio

MFCD00006638

2,2-Dimethyl-4,6-diketo-1,3-dioxane

EINECS 217-992-8

Meldrum acid

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Meldrumic acid
Price: ￥155.0/100g ￥505.0/500g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: AI3-39039
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,2-Dimethyl-1,3-dioxane-4,6-dione TOP1 supplier
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2,2-Dimethyl-1,3-dioxane-4,6-dione
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Meldrum's acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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