Ligustilide structure
|
Common Name | Ligustilide | ||
|---|---|---|---|---|
| CAS Number | 4431-01-0 | Molecular Weight | 190.238 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 377.9±11.0 °C at 760 mmHg | |
| Molecular Formula | C12H14O2 | Melting Point | 297-298ºC | |
| MSDS | Chinese USA | Flash Point | 158.6±16.7 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of LigustilideLigustilide is an effective constituent extracted from Angelica sinensis.IC50 value:Target:In vitro: To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide [1].In vivo: |
| Name | Ligustilide |
|---|---|
| Synonym | More Synonyms |
| Description | Ligustilide is an effective constituent extracted from Angelica sinensis.IC50 value:Target:In vitro: To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide [1].In vivo: |
|---|---|
| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 377.9±11.0 °C at 760 mmHg |
| Melting Point | 297-298ºC |
| Molecular Formula | C12H14O2 |
| Molecular Weight | 190.238 |
| Flash Point | 158.6±16.7 °C |
| Exact Mass | 190.099380 |
| PSA | 26.30000 |
| LogP | 2.63 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.545 |
| InChIKey | IQVQXVFMNOFTMU-FLIBITNWSA-N |
| SMILES | CCCC=C1OC(=O)C2=C1CCC=C2 |
| 3-BUTYLIDENE-4,5-DIHYDROPHTHALIDE |
| 3-BUTYLIDEN-4,5-DIHYDRO-3H-ISOBENZOFURAN-1-ONE |
| Ligustilide |
| 3-Butyliden-1-oxo-1.3.4.5-tetrahydro-isobenzofuran |
| Angelica Extract Powder |
| LIGUSTILIDE,Z |
| cis-ligustilide |
| Ligustilide, (Z)- |
| 1(3H)-Isobenzofuranone, 3-butylidene-4,5-dihydro-, (3Z)- |
| Z-LIGUSTILIDE |
| (3Z)-3-Butylidene-4,5-dihydro-2-benzofuran-1(3H)-one |
| 3-butylidene-4,5-dihydro-3H-isobenzofuran-1-one |