5a-androstane

Modify Date: 2024-01-02 08:47:25

5a-androstane Structure
5a-androstane structure
Common Name 5a-androstane
CAS Number 438-22-2 Molecular Weight 260.457
Density 0.9±0.1 g/cm3 Boiling Point 336.0±9.0 °C at 760 mmHg
Molecular Formula C19H32 Melting Point 78-82 °C(lit.)
MSDS Chinese USA Flash Point 145.9±12.3 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Names

Name 5α-androstane
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 336.0±9.0 °C at 760 mmHg
Melting Point 78-82 °C(lit.)
Molecular Formula C19H32
Molecular Weight 260.457
Flash Point 145.9±12.3 °C
Exact Mass 260.250397
LogP 8.42
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.508
Storage condition -20℃

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H315-H319-H335-H336-H351-H373
Precautionary Statements P261-P281-P305 + P351 + P338
Target Organs Blood, Central nervous system, Liver
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T: Toxic;
Risk Phrases 45-23/24/25-36/37/38-43-63
Safety Phrases S53-S23-S24/25-S36/37
RIDADR UN 1593 6.1/PG 3
WGK Germany 3

 Synthetic Route

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5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Butenandt; Tscherning Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 185,190 Full Text Show Details Heard; McKay Journal of Biological Chemistry, 1939 , vol. 131, p. 371,378 Full Text Show Details Reichstein Helvetica Chimica Acta, 1936 , vol. 19, p. 979,983

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5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Burrows et al. Biochemical Journal, 1937 , vol. 31, p. 950,957

~%

5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Burrows et al. Biochemical Journal, 1937 , vol. 31, p. 950,957

~%

5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Burrows et al. Biochemical Journal, 1937 , vol. 31, p. 950,957

~%

5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Butenandt; Tscherning Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 229, p. 185,190

~%

5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Kaegi; Miescher Helvetica Chimica Acta, 1939 , vol. 22, p. 683,695 Full Text Show Details Prelog; Ruzicka; Wieland Helvetica Chimica Acta, 1944 , vol. 27, p. 66,69

~%

5a-androstane Structure

5a-androstane

CAS#:438-22-2

Literature: Reichstein Helvetica Chimica Acta, 1936 , vol. 19, p. 979,983

 Articles24

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17beta-Hydroxysteroid dehydrogenase type 7 (17beta-HSD7) catalyzes the reduction of estrone (E(1)) into estradiol (E(2)) and of dihydrotestosterone (DHT) into 5alpha-androstane-3beta,17beta-diol (3bet...

Novel and efficient synthesis and antifungal evaluation of 2,3-functionalized cholestane and androstane derivatives

Bioorg. Med. Chem. Lett. 20 , 7372-5, (2010)

Synthetic modifications of cholesterol and other traditional steroid molecules have become a promising area for the exploration and development of novel antifungal agents, especially with respect to t...

[Bioconversion of C19- and C21-steroids with parent and mutant strains of Curvularia lunata].

Prikl. Biokhim. Mikrobiol. 46(2) , 212-20, (2010)

Regio- and stereospecificity of microbial hydroxylation was studied at the transformation of 3-keto-4-ene steroids of androstane and pregnane series by the filamentous fungus of Curvularia lunata VKMF...

 Synonyms

Aetioallocholane
5α-Androstan
5alpha-Androstane
MFCD00067600
(5a)-Androstane
(5α)-Androstane
Etioallocholane
(5R,8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene
5α,14α-Androstane
5a-androstane
EINECS 207-116-2
Aetioallocholan
Androstane, (5α)-
5α-androstane
Androstane